Projects per year
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Collaborations and top research areas from the last five years
Projects
- 7 Finished
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Poly(ADP-ribose) promotes the condensation and toxicity of C9orf72 arginine-rich dipeptide repeat proteins
Zhang, Y. (PI), Gendron, T. D. (CoPI) & Zhang, K. (CoPI)
National Institute of Neurological Disorders and Stroke
7/15/21 → 6/30/24
Project: Research project
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Frontotemporal dementia and related disorders: transcriptomic profiling, biomarker discovery, and mechanistic insight
Van Blitterswijk, M. (PI) & Gendron, T. D. (CoPI)
National Institute of Neurological Disorders and Stroke
4/15/21 → 3/31/25
Project: Research project
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Core C
Gendron, T. D. (PI)
National Institute of Neurological Disorders and Stroke
4/1/20 → 3/31/25
Project: Research project
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Pathobiology of Neurodegeneration in C9ORF72 repeat expansion
Petrucelli, L. (PI), Oskarsson, B. (CoPI), Fryer, J. D. (CoPI), Gendron, T. D. (CoPI), Boylan, K. B. (CoPI) & Dickson, D. W. (CoPI)
National Institute of Neurological Disorders and Stroke
9/30/14 → 3/31/25
Project: Research project
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c9RAN proteins as a biomarker for C9ORF72-associated ALS and FTD
Gendron, T. D. (PI) & Boylan, K. B. (CoPI)
National Institute of Neurological Disorders and Stroke
9/15/14 → 8/31/17
Project: Research project
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Clinical and neuropathological associations of plasma Aβ42/Aβ40, p-tau217 and neurofilament light in sporadic frontotemporal dementia spectrum disorders
for the ALLFTD Consortium, Jan 1 2025, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 17, 1, e70078.Research output: Contribution to journal › Article › peer-review
Open Access -
Proteomic analysis of carotid artery plaques with and without vulnerable features on magnetic resonance angiography with vessel wall imaging: a pilot study
Madden, B. J., Polania-Sandoval, C., Pujari, G. P., Mangalaparthi, K. K., Charlesworth, M. C., Prudencio, M., Gendron, T., Sandhu, S. J. S., Nassar, A., Petrucelli, L., Meschia, J. F., Pandey, A. & Erben, Y., Jan 2025, In: JVS-Vascular Science. 6, 100281.Research output: Contribution to journal › Article › peer-review
Open Access -
pTDP-43 levels correlate with cell type–specific molecular alterations in the prefrontal cortex of C9orf72 ALS/FTD patients
Wang, H. L. V., Xiang, J. F., Yuan, C., Veire, A. M., Gendron, T. F., Murray, M. E., Tansey, M. G., Hu, J., Gearing, M., Glass, J. D., Jin, P., Corces, V. G. & McEachin, Z. T., Mar 4 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 9, e2419818122.Research output: Contribution to journal › Article › peer-review
Open Access -
Abundant transcriptomic alterations in the human cerebellum of patients with a C9orf72 repeat expansion
Udine, E., DeJesus-Hernandez, M., Tian, S., das Neves, S. P., Crook, R., Finch, N. C. A., Baker, M. C., Pottier, C., Graff-Radford, N. R., Boeve, B. F., Petersen, R. C., Knopman, D. S., Josephs, K. A., Oskarsson, B., Da Mesquita, S., Petrucelli, L., Gendron, T. F., Dickson, D. W., Rademakers, R. V. & van Blitterswijk, M., Jun 2024, In: Acta neuropathologica. 147, 1, 73.Research output: Contribution to journal › Article › peer-review
Open Access -
Apilimod dimesylate in C9orf72 amyotrophic lateral sclerosis: a randomized phase 2a clinical trial
Babu, S., Nicholson, K. A., Rothstein, J. D., Swenson, A., Sampognaro, P. J., Pant, P., Macklin, E. A., Spruill, S., Paganoni, S., Gendron, T. F., Prudencio, M., Petrucelli, L., Nix, D., Landrette, S., Nkrumah, E., Fandrick, K., Edwards, J. & Young, P. R., Sep 1 2024, In: Brain. 147, 9, p. 2998-3008 11 p.Research output: Contribution to journal › Article › peer-review