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Dive into the research topics where Leonard Petrucelli is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
- 2 Active
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Mayo Alzheimer's Disease Research Center
Petersen, R. R. C. (PI), Bu, G. D. (CoPI), Boeve, B. (CoPI), Dickson, D. W. (CoPI), Jones, D. T. (CoPI), Kantarci, K. M. (CoPI), Knopman, D. S. (CoPI), Kremers, W. K. (CoPI), Petrucelli, L. (CoPI), Lucas, J. A. (CoPI), Ertekin-Taner, N. (CoPI) & McLean, P. J. (CoPI)
7/1/19 → 4/30/25
Project: Research project
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Pathobiology of Neurodegeneration in C9ORF72 repeat expansion
Petrucelli, L. (PI), Oskarsson, B. (CoPI), Fryer, J. D. (CoPI), Gendron, T. D. (CoPI), Boylan, K. B. (CoPI), Dickson, D. W. (CoPI), Gendron, T. T. F. (CoPI), Oskarsson, B. E. (CoPI) & Petrucelli, L. (CoPI)
National Institute of Neurological Disorders and Stroke
9/30/14 → 3/31/25
Project: Research project
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Abundant transcriptomic alterations in the human cerebellum of patients with a C9orf72 repeat expansion
Udine, E., DeJesus-Hernandez, M., Tian, S., das Neves, S. P., Crook, R., Finch, N. C. A., Baker, M. C., Pottier, C., Graff-Radford, N. R., Boeve, B. F., Petersen, R. C., Knopman, D. S., Josephs, K. A., Oskarsson, B., Da Mesquita, S., Petrucelli, L., Gendron, T. F., Dickson, D. W., Rademakers, R. & van Blitterswijk, M., Jun 2024, In: Acta neuropathologica. 147, 1, 73.Research output: Contribution to journal › Article › peer-review
Open Access -
Artificial microRNA suppresses C9ORF72 variants and decreases toxic dipeptide repeat proteins in vivo
Cabrera, G. T., Meijboom, K. E., Abdallah, A., Tran, H., Foster, Z., Weiss, A., Wightman, N., Stock, R., Gendron, T., Gruntman, A., Giampetruzzi, A., Petrucelli, L., Brown, R. H. & Mueller, C., Mar 2024, In: Gene Therapy. 31, 3-4, p. 105-118 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Clinicopathologic features of a novel star-shaped transactive response DNA-binding protein 43 (TDP-43) pathology in the oldest old
Carlos, A. F., Sekiya, H., Koga, S., Gatto, R. G., Casey, M. C., Pham, N. T. T., Sintini, I., Machulda, M. M., Jack, C. R., Lowe, V. J., Whitwell, J. L., Petrucelli, L., Reichard, R. R., Petersen, R. C., Dickson, D. W. & Josephs, K. A., Jan 1 2024, In: Journal of Neuropathology and Experimental Neurology. 83, 1, p. 36-52 17 p.Research output: Contribution to journal › Article › peer-review
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Correction to: HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases (Molecular Neurodegeneration, (2024), 19, 1, (29), 10.1186/s13024-024-00718-8)
Calliari, A., Daughrity, L. M., Albagli, E. A., Castellanos Otero, P., Yue, M., Jansen-West, K., Islam, N. N., Caulfield, T., Rawlinson, B., DeTure, M., Cook, C., Graff-Radford, N. R., Day, G. S., Boeve, B. F., Knopman, D. S., Petersen, R. C., Josephs, K. A., Oskarsson, B., Gitler, A. D. & Dickson, D. W. & 5 others, , Dec 2024, In: Molecular neurodegeneration. 19, 1, 56.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Cryo-EM structures of pathogenic fibrils and their impact on neurodegenerative disease research
Todd, T. W., Islam, N. N., Cook, C. N., Caulfield, T. R. & Petrucelli, L., Jul 17 2024, In: Neuron. 112, 14, p. 2269-2288 20 p.Research output: Contribution to journal › Review article › peer-review