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Dive into the research topics where Leonard Petrucelli is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Investigating the role of TMEM106b genetics and pathology in Alzheimer’s disease, LATE and FTLD
Petrucelli, L. (PI) & Josephs, K. A. (CoPI)
National Institute of Neurological Disorders and Stroke
9/22/23 → 8/31/25
Project: Research project
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Alzheimer's Disease Tau Core-based Mouse Models and RT-QuiC Biomarker Assay.
Petrucelli, L. (PI)
1/1/21 → …
Project: Research project
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Novel genetic modifiers of C9orf72 and Tau toxicity
Fryer, J. D. (PI) & Petrucelli, L. (CoPI)
8/15/20 → 3/31/24
Project: Research project
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Admin Core
Petrucelli, L. (PI)
National Institute of Neurological Disorders and Stroke
4/1/20 → 3/31/25
Project: Research project
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Project 2
Petrucelli, L. (PI)
National Institute of Neurological Disorders and Stroke
4/1/20 → 3/31/25
Project: Research project
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Artificial enforcement of the unfolded protein response reduces disease features in multiple preclinical models of ALS/FTD
Valenzuela, V., Becerra, D., Astorga, J. I., Fuentealba, M., Diaz, G., Bargsted, L., Chacón, C., Martinez, A., Gozalvo, R., Jackson, K., Morales, V., Heras, M. L., Tamburini, G., Petrucelli, L., Sardi, S. P., Plate, L. & Hetz, C., Mar 5 2025, In: Molecular Therapy. 33, 3, p. 1226-1245 20 p.Research output: Contribution to journal › Article › peer-review
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Clinical and neuropathological associations of plasma Aβ42/Aβ40, p-tau217 and neurofilament light in sporadic frontotemporal dementia spectrum disorders
for the ALLFTD Consortium, Jan 1 2025, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 17, 1, e70078.Research output: Contribution to journal › Article › peer-review
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Evaluating Glial Fibrillary Acidic Protein and Neurofilament Light as Potential Biomarkers for Spinocerebellar Ataxia 7
Hanna Al-Shaikh, R., Jansen-West, K., Strongosky, A., Parrales, Z., Dunmore, J. A., Song, Y., Gendron, T. F., Guevara, J. C., Teive, H. A. G., Dulski, J., Sławek, J., Petrucelli, L., Wszolek, Z. K. & Prudencio, M., Jun 2025, In: International journal of molecular sciences. 26, 11, 5070.Research output: Contribution to journal › Article › peer-review
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Lipidomic Expression Analysis in Carotid Atherosclerotic Disease: A Systematic Review
Polania-Sandoval, C., Byeon, S. K., Hartwell, J., Prudencio, M., Petrucelli, L., Brigham, T., Meschia, J. F., Pandey, A. & Erben, Y., Apr 2025, In: Annals of Vascular Surgery. 113, p. 83-94 12 p.Research output: Contribution to journal › Review article › peer-review
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Physiological shedding and C-terminal proteolytic processing of TMEM106B
Held, S., Erck, C., Kemppainen, S., Bleibaum, F., Giridhar, N. J., Feederle, R., Krenner, C., Juopperi, S. P., Calliari, A., Mentrup, T., Schröder, B., Dickson, D. W., Rauramaa, T., Petrucelli, L., Prudencio, M., Hiltunen, M., Lüningschrör, P., Capell, A. & Damme, M., Jan 28 2025, In: Cell reports. 44, 1, 115107.Research output: Contribution to journal › Article › peer-review
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