Projects per year
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Collaborations and top research areas from the last five years
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Mouse models of sense and antisense C9orf72 transcripts
Zhang, Y. (PI)
1/1/15 → …
Project: Research project
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Generation and Characterization of M337V TDP-43 Transgenic Mice: A Possible Model For TDP-43 Proteinopathy
Zhang, Y. (PI)
American Federation for Aging Research
1/1/09 → …
Project: Research project
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Poly(ADP-ribose) promotes the condensation and toxicity of C9orf72 arginine-rich dipeptide repeat proteins
Zhang, Y. (PI), Gendron, T. T. F. (CoPI), Gendron, T. D. (CoPI), Zhang, K. (CoPI) & Zhang, Y. (CoPI)
National Institute of Neurological Disorders and Stroke
7/15/21 → 6/30/24
Project: Research project
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Understanding the Mechanisms of TDP-43 Function
Zhang, Y. (PI) & Fryer, J. D. (CoPI)
National Institute of Neurological Disorders and Stroke
2/15/13 → 1/31/16
Project: Research project
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Correction to: HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases (Molecular Neurodegeneration, (2024), 19, 1, (29), 10.1186/s13024-024-00718-8)
Calliari, A., Daughrity, L. M., Albagli, E. A., Castellanos Otero, P., Yue, M., Jansen-West, K., Islam, N. N., Caulfield, T., Rawlinson, B., DeTure, M., Cook, C., Graff-Radford, N. R., Day, G. S., Boeve, B. F., Knopman, D. S., Petersen, R. C., Josephs, K. A., Oskarsson, B., Gitler, A. D. & Dickson, D. W. & 5 others, , Dec 2024, In: Molecular neurodegeneration. 19, 1, 56.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Generation and characterization of monoclonal antibodies against pathologically phosphorylated TDP-43
Otero, P. C., Todd, T. W., Shao, W., Jones, C. J., Huang, K., Daughrity, L. M., Yue, M., Sheth, U., Gendron, T. F., Prudencio, M., Oskarsson, B., Dickson, D. W., Petrucelli, L. & Zhang, Y. J., Apr 2024, In: PloS one. 19, 4 April, e0298080.Research output: Contribution to journal › Article › peer-review
Open Access -
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases
Calliari, A., Daughrity, L. M., Albagli, E. A., Castellanos Otero, P., Yue, M., Jansen-West, K., Islam, N. N., Caulfield, T., Rawlinson, B., DeTure, M., Cook, C., Graff-Radford, N. R., Day, G. S., Boeve, B. F., Knopman, D. S., Petersen, R. C., Josephs, K. A., Oskarsson, B., Gitler, A. D. & Dickson, D. W. & 5 others, , Dec 2024, In: Molecular neurodegeneration. 19, 1, 29.Research output: Contribution to journal › Letter › peer-review
Open Access -
Mis-spliced transcripts generate de novo proteins in TDP-43–related Als/FTD
Seddighi, S., Qi, Y. A., Brown, A. L., Wilkins, O. G., Bereda, C., Belair, C., Zhang, Y. J., Prudencio, M., Keuss, M. J., Khandeshi, A., Pickles, S., Kargbo-Hill, S. E., Hawrot, J., Ramos, D. M., Yuan, H., Roberts, J., Sacramento, E. K., Shah, S. I., Nalls, M. A. & Colón-Mercado, J. M. & 31 others, , 2024, In: Science translational medicine. 16, 734, eadg7162.Research output: Contribution to journal › Article › peer-review
Open Access -
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia
Marks, J. D., Ayuso, V. E., Carlomagno, Y., Yue, M., Todd, T. W., Hao, Y., Li, Z., McEachin, Z. T., Shantaraman, A., Duong, D. M., Daughrity, L. M., Jansen-West, K., Shao, W., Calliari, A., Bejarano, J. G., DeTure, M., Rawlinson, B., Casey, M. C., Lilley, M. T. & Donahue, M. H. & 16 others, , Jan 17 2024, In: Science translational medicine. 16, 730, eadf9735.Research output: Contribution to journal › Article › peer-review
Open Access