Rochester, MN

Projects

Projects per year 1984 2009 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 376 Active
• 1198 Finished

Projects per year

Search results

• Active

  Project 3

  Degnim, A. C.

  National Cancer Institute

  9/1/23 → 8/31/24

  Project: Research project

  • Vaccines 100%
  • Antigens 42%
  • Clinical Trials 36%
  • Breast 25%
  • Breast Neoplasms 21%

• Project 2

  Goetz, M. P.

  National Cancer Institute

  9/1/23 → 8/31/24

  Project: Research project

  • 4-hydroxy-N-desmethyltamoxifen 100%
  • Survival 7%
  • Endocrine System Diseases 5%
  • Neoadjuvant Therapy 5%

• Developmental Research Program

  Vachon, C. M.

  National Cancer Institute

  9/1/23 → 8/31/24

  Project: Research project

  • myeloma 100%
  • research programs 65%
  • funding 32%
  • research projects 21%
  • translational medical research 15%

• CRCNS: Deep Learning to Discover Neurovascular Disruptions in Alzheimer's Disease

  Kandimalla, K. K., Fernandez -granda, C. C., Kalari, K. R. & Hernaez, M.

  National Institute on Aging

  9/1/23 → 5/31/24

  Project: Research project

• Robert Wood Johnson Foundation Health Policy Fellows -- Grace Lin, MD, MBA

  Lin, G. D.

  Robert Wood Johnson Foundation

  9/1/23 → 8/31/25

  Project: Research project

• A new model for spatio-temporal coupling of bone formation and bone resorption governed by osteoclasts

  Mishina, Y. Y., Park, D. & Weivoda, M.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  9/1/23 → 8/31/24

  Project: Research project

  • bone 100%
  • resorption 82%
  • cell 30%
  • communication 28%
  • animal 8%

• Cancer Adoptive Cell Therapy (Can-ACT) Network Coordinating Center at Mayo Clinic

  Geyer, S. & Asmann, Y.

  National Cancer Institute

  9/1/23 → 8/31/24

  Project: Research project

  • Cell- and Tissue-Based Therapy 100%
  • Neoplasms 37%
  • Data Science 36%
  • Psychological Identification 32%
  • Financial Management 30%

• CD38 modulation of NAD metabolism driving scleroderma pathogenesis

  Varga, J. & Chini, E. N.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  9/1/23 → 8/31/24

  Project: Research project

  • Nicotinamide N-Methyltransferase 100%
  • Systemic Scleroderma 63%
  • NAD 49%
  • Niacinamide 25%
  • Fibrosis 22%

• Electrical stimulation to control feedback modulation of perception

  Hermes Miller, D., Worrell, G. A. & Kay, K. K. N.

  National Eye Institute

  9/1/23 → 6/30/24

  Project: Research project

  • Temporal Lobe 100%
  • Electric Stimulation 65%
  • Electrodes 30%
  • Visual Perception 29%
  • Parietal Lobe 23%

• Clinical benefits and mechanism of action of angiotensin-II receptor blocker on Cardiovascular remodeling in patients with repaired coarctation of aorta

  Egbe, A.

  National Heart, Lung, and Blood Institute

  8/25/23 → 7/31/24

  Project: Research project

  • Aortic Coarctation 100%
  • Angiotensin Receptor Antagonists 54%
  • Ventricular Remodeling 40%
  • Hypertension 37%
  • Left Ventricular Dysfunction 36%

• In vivo SELEX strategies to identify potent aptamer-drug conjugates for glioblastoma

  Sarkaria, J. N. & Maher, L. L. J.

  National Institute of Neurological Disorders and Stroke

  8/21/23 → 7/31/24

  Project: Research project

  • SELEX Aptamer Technique 100%
  • Glioblastoma 80%
  • Libraries 38%
  • Nucleotide Aptamers 37%
  • Pharmaceutical Preparations 20%

• Venous Thrombosis After Traumatic Injury

  Park, M. S. & Auton, M. T.

  National Heart, Lung, and Blood Institute

  8/15/23 → 7/31/24

  Project: Research project

  • Venous Thrombosis 100%
  • Wounds and Injuries 93%
  • Venous Thromboembolism 39%
  • Quality of Health Care 31%
  • Thrombosis 28%

• Quantitative characterization of the liver-pancreas axis in diabetes via multiparametric magnetic resonance elastography

  Yin, M.

  National Institute of Diabetes and Digestive and Kidney Diseases

  8/9/23 → 4/30/24

  Project: Research project

  • Elasticity Imaging Techniques 100%
  • Non-alcoholic Fatty Liver Disease 82%
  • Pancreas 70%
  • Liver 47%
  • Prediabetic State 28%

• Atraumatic Non-fibrotic Epicardial Pacing with E-Bioadhesive Devices

  Zhao, X. & Griffiths, L.

  National Heart, Lung, and Blood Institute

  8/1/23 → 7/31/24

  Project: Research project

  • Equipment Failure 100%
  • Thoracic Surgery 96%
  • Pericardium 80%
  • Bradycardia 74%
  • Equipment and Supplies 73%

• Mass spectrometry for highly sensitive and sample-sparing analysis of extracellular vesicles in liver diseases

  Revzin, A. & Schweikert, E. A.

  National Institute of Diabetes and Digestive and Kidney Diseases

  8/1/23 → 5/31/24

  Project: Research project

  • Extracellular Vesicles 100%
  • Fatty Liver 84%
  • Non-alcoholic Fatty Liver Disease 56%
  • Mass Spectrometry 54%
  • Liver Diseases 51%

• Rapid, simple, and ultrasensitive quantitation of KRAS ctDNA at the point of care using CRISPR/Cas amplification and digital resolution biosensor microscopy

  Cunningham, B. B. T., Mansfield, A. & Wang, X. X.

  National Cancer Institute

  8/1/23 → 7/31/24

  Project: Research project

  • Circulating Tumor DNA 100%
  • Biosensing Techniques 67%
  • Clustered Regularly Interspaced Short Palindromic Repeats 55%
  • Point-of-Care Systems 54%
  • Optics and Photonics 48%

• Biological Analysis Core

  LeBrasseur, N. K.

  National Institute on Aging

  8/1/23 → 7/31/24

  Project: Research project

  • Atlases 100%
  • Biomarkers 45%
  • Proteomics 42%
  • Mass Spectrometry 41%
  • Skeletal Muscle 36%

• Uncover mechanisms underlying the development of chronic lung sequelae post COVID-19

  Sun, J. & Vassallo, R.

  National Heart, Lung, and Blood Institute

  8/1/23 → 7/31/24

  Project: Research project

  • Lung 100%
  • SARS Virus 64%
  • Systems Biology 26%
  • Population Characteristics 26%
  • Bronchoalveolar Lavage Fluid 23%

• ATR: targeting mechanical stress induced EMT and immune suppression in triple negative breast cancer

  Mutter, R. R. W. & Lou, Z.

  National Cancer Institute

  8/1/23 → 7/31/24

  Project: Research project

  • Epithelial-Mesenchymal Transition 100%
  • Triple Negative Breast Neoplasms 96%
  • Mechanical Stress 92%
  • Nuclear Matrix 46%
  • Cytoskeleton 45%

• Novel diagnostic stimulation to quantify cortical excitability and guide epilepsy therapy

  Lundstrom, B.

  National Institute of Neurological Disorders and Stroke

  8/1/23 → 7/31/24

  Project: Research project

  • Cortical Excitability 100%
  • Epilepsy 85%
  • Biomarkers 84%
  • Seizures 71%
  • Electroencephalography 47%

• MRI Core

  Jack, C. R. J.

  National Institute on Aging

  8/1/23 → 7/31/24

  Project: Research project

  • Vascular Diseases 100%
  • Diffusion Magnetic Resonance Imaging 80%
  • Dementia 57%
  • Perfusion 51%
  • Clinical Trials 44%

• Cell-extrinsic emergency myelopoiesis regulated by ABCB7

  Shapiro, V. M. & Medina, K. L.

  National Heart, Lung, and Blood Institute

  7/15/23 → 6/30/24

  Project: Research project

  • Myelopoiesis 100%
  • Emergencies 43%
  • Bone Marrow 26%
  • B-Lymphoid Precursor Cells 26%
  • Erythropoiesis 25%

• Harnessing the latent heat of saline evaporation for safe and effective endovascular therapeutic organ cooling

  Kallmes, D. F.

  National Institute of Neurological Disorders and Stroke

  7/15/23 → 6/30/25

  Project: Research project

  • Thrombectomy 100%
  • Catheters 54%
  • Hot Temperature 53%
  • Cold Temperature 37%
  • Neuroprotective Agents 28%

• Immune Outcomes to Neonatal Antigen Delivery in the Intestine

  Knoop, K.

  National Institute of Diabetes and Digestive and Kidney Diseases

  7/15/23 → 4/30/24

  Project: Research project

  • Antigens 100%
  • Intestines 81%
  • Epidermal Growth Factor 68%
  • Regulatory T-Lymphocytes 34%
  • Antigen-Presenting Cells 24%

• The Mayo Clinic NeuroNEXT Clinical Research Site

  Staff, N. P.

  National Institute of Neurological Disorders and Stroke

  7/15/23 → 6/30/24

  Project: Research project

  • Clinical Trials 100%
  • Neurology 97%
  • Organized Financing 72%
  • Neurologists 34%
  • Neurosciences 32%

• Altered TCR signaling in anergy

  Shapiro, V. M.

  National Institute of Allergy and Infectious Diseases

  7/6/23 → 6/30/24

  Project: Research project

  • T-Lymphocytes 100%
  • Knockout Mice 17%
  • Interleukin-2 16%
  • Core Binding Factor Alpha 2 Subunit 16%
  • ras GTPase-Activating Proteins 14%

• Pathobiology of liver fibrosis

  Enis, K.

  National Institute of Diabetes and Digestive and Kidney Diseases

  7/1/23 → 4/30/24

  Project: Research project

  • Glycolysis 100%
  • Liver Cirrhosis 88%
  • Proto-Oncogene Proteins c-sis 68%
  • Liver 45%
  • Acetyl Coenzyme A 20%

• Elucidating the Role and Regulation of Proteostasis in Hepatic Fibrogenesis

  Maiers, J.

  National Institute of Diabetes and Digestive and Kidney Diseases

  7/1/23 → 4/30/24

  Project: Research project

  • Hepatic Stellate Cells 100%
  • Proteostasis 76%
  • Unfolded Protein Response 28%
  • Liver 25%
  • Fibrosis 17%

• A phase I/II study of combined therapy with Th17-inducing dendritic cells and pembrolizumab in patients with recurrent epithelial ovarian cancer

  Knutson, K. L. & Block, M. S.

  National Cancer Institute

  7/1/23 → 6/30/24

  Project: Research project

  • pembrolizumab 100%
  • Ovarian Epithelial Carcinoma 82%
  • Dendritic Cells 63%
  • Th17 Cells 53%
  • Vaccines 50%

• Extracellular vesicle-based senotherapeutics for aging diabetic kidneydisease

  Hickson, L. & Wolfram, J.

  National Institute on Aging

  6/1/23 → 2/29/24

  Project: Research project

  • Extracellular Vesicles 100%
  • Diabetic Nephropathies 90%
  • Kidney 27%
  • Inflammation 23%
  • Longevity 17%

• Pulmonary Hypertension in Left Heart Disease

  Redfield, M. M. & Borlaug, B. A.

  National Heart, Lung, and Blood Institute

  6/1/23 → 5/31/24

  Project: Research project

  • Pulmonary Hypertension 100%
  • Lung 86%
  • Heart Diseases 81%
  • Vascular Remodeling 71%
  • Vascular Diseases 39%

• Linking epigenetics to electrophysiology using high-throughput microelectrode array-based hardware with simultaneous optogenetic activation

  Petersen, R. C.

  NIH Office of the Director

  6/1/23 → 5/31/24

  Project: Research project

  • Microelectrodes 100%
  • Electrophysiology 87%
  • Optogenetics 87%
  • Epigenomics 78%
  • Organoids 58%

• Pre-transplant health coaching to improve patient-reported outcomes in lung transplant candidates

  Kennedy, C.

  National Heart, Lung, and Blood Institute

  5/1/23 → 4/30/24

  Project: Research project

• Genomics of Alcohol Withdrawal and Treatment Response to Benzodiazepines

  Karpyak, V. M. & Biernacka, J. M.

  National Institute on Alcohol Abuse and Alcoholism

  5/1/23 → 4/30/24

  Project: Research project

  • Alcohols 100%
  • Benzodiazepines 73%
  • Genomics 72%
  • Alcoholism 68%
  • Genome 36%

• Exercise Response in Humans with Obesity

  Lanza, I. R.

  National Institute of Diabetes and Digestive and Kidney Diseases

  5/1/23 → 4/30/24

  Project: Research project

  • Adipose Tissue 100%
  • Subcutaneous Fat 67%
  • Obesity 50%
  • Skeletal Muscle 47%
  • Exercise 23%

• Hybrid approach for comprehensive mutation detection in a cell

  Abyzov, A.

  National Institute of Neurological Disorders and Stroke

  4/15/23 → 3/31/24

  Project: Research project

  • mutation 100%
  • cells 75%
  • genome 62%
  • cloning (cells) 57%
  • molecular cloning 42%

• International Consortium for the Genetics of Biliary Tract Cancers Cholangiocarcinoma Genome Wide Association Study

  Roberts, L. R., Amos, C. I. & Hassan, M. M. M.

  National Cancer Institute

  4/10/23 → 3/31/24

  Project: Research project

  • Sclerosing Cholangitis 100%
  • Biliary Tract Neoplasms 69%
  • Genome-Wide Association Study 66%
  • Cholangiocarcinoma 56%
  • Bile Ducts 20%

• Noninvasive assessment of portal hypertension and hepatic interstitial pressure with advanced magnetic resonance elastography

  Yin, M.

  National Institute of Diabetes and Digestive and Kidney Diseases

  4/1/23 → 1/31/24

  Project: Research project

  • Portal Hypertension 100%
  • Elasticity Imaging Techniques 91%
  • Liver 44%
  • Pressure 42%
  • Fibrosis 31%

• Development of novel therapeutics for cancer cachexia

  Ebert, S., Judge, A. R., Adams, C., Talley, J. J. & Judge, S. M.

  National Cancer Institute

  4/1/23 → 3/31/24

  Project: Research project

  • Cachexia 100%
  • Muscular Atrophy 85%
  • Muscle Neoplasms 64%
  • Neoplasms 46%
  • Skeletal Muscle 33%

• Heme-mediated Mitochondrial Injury, Senescence, Acute Kidney Injury and Chronic Kidney Disease

  Nath, K. A.

  National Institute of Diabetes and Digestive and Kidney Diseases

  3/15/23 → 1/31/24

  Project: Research project

  • Acute Kidney Injury 100%
  • Heme 93%
  • Hemeproteins 56%
  • Chronic Renal Insufficiency 51%
  • Wounds and Injuries 39%

• A Novel Melanoma Vaccine Based on a Shared Neoantigen and a Liquid Polymer Platform

  Wang, C. C. & Block, M. S.

  National Cancer Institute

  3/1/23 → 2/29/24

  Project: Research project

  • Vaccines 100%
  • Melanoma 97%
  • HLA-A2 Antigen 87%
  • Polymers 68%
  • resiquimod 51%

• Evaluation of novel tomosynthesis density measures in breast cancer risk prediction

  Vachon, C. M., Kontos, D. & Kerlikowske, K. K. M.

  National Cancer Institute

  3/1/23 → 2/29/24

  Project: Research project

  • Mammography 100%
  • Breast Neoplasms 48%
  • Breast Density 16%
  • Artificial Intelligence 15%
  • X-Rays 9%

• Aak1 to increase infiltration of adoptively transferred cells into solid tumors

  Rogers, L.

  National Cancer Institute

  2/16/23 → 1/31/24

  Project: Research project

  • Phosphotransferases 100%
  • T-Lymphocytes 85%
  • Adoptive Transfer 59%
  • Neoplasms 38%
  • Chemotaxis 36%

• PHLPP inhibition and Osteoarthritis-Associated Pain

  Westendorf, J. J. & Staff, N. P.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  2/1/23 → 12/31/23

  Project: Research project

  • Sensory Receptor Cells 100%
  • Joints 82%
  • Osteoarthritis 62%
  • Pain 60%
  • Psychological Inhibition 57%

• Synthetic Lethal Targeting of SETD2 in Renal Cell Carcinoma

  Robertson, K. D. & Ho, T. H.

  National Cancer Institute

  2/1/23 → 1/31/24

  Project: Research project

  • Synthetic Lethal Mutations 100%
  • Epigenomics 99%
  • Renal Cell Carcinoma 76%
  • Drive 70%
  • Phenotype 40%

• Role of PAPP-A in Graves' Ophthalmopathy

  Conover, C. A.

  National Institute of Allergy and Infectious Diseases

  1/18/23 → 12/31/23

  Project: Research project

  • Pregnancy-Associated Plasma Protein-A 100%
  • Graves Ophthalmopathy 52%
  • IGF Type 1 Receptor 31%
  • Insulin-Like Growth Factor Binding Protein 4 25%
  • Fibroblasts 18%

• Role of mitochondrial microRNAs (mitomiRs) in endogenous renal repair

  Eirin, A.

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/1/23 → 11/30/23

  Project: Research project

  • Renal Artery Obstruction 100%
  • MicroRNAs 71%
  • Kidney 39%
  • Swine 26%
  • Epigenomics 19%

• Investigating the role of MAP2 in chemotherapy-induced peripheral neurotoxicity

  Staff, N. P.

  National Cancer Institute

  1/1/23 → 12/31/23

  Project: Research project

  • Microtubule-Associated Proteins 100%
  • Bortezomib 47%
  • Induced Pluripotent Stem Cells 44%
  • Axonal Transport 32%
  • Drug Therapy 31%

• Hydrogen Sulfide in Neonatal Airway Disease

  Pabelick, C. M. & Prakash, Y. S.

  National Heart, Lung, and Blood Institute

  1/1/23 → 11/30/23

  Project: Research project

  • Infant, Newborn, Diseases 100%
  • Hydrogen Sulfide 91%

• Development of an ultrasound detectable, migration-resistant biopsy marker for improving care in patients with breast cancer

  Urban, M. W. & Lee, C. U.

  National Institute of Biomedical Imaging and Bioengineering

  12/15/22 → 11/30/23

  Project: Research project

  • Breast Neoplasms 100%
  • Patient Care 88%
  • Lymph Nodes 81%
  • Biopsy 77%
  • Swine 45%