Change in consumption patterns for treatment-seeking patients with alcohol use disorder post-bariatric surgery

Alfredo B. Cuellar-Barboza, Mark A. Frye, Karen Grothe, Miguel L. Prieto, Terry D. Schneekloth, Larissa L. Loukianova, K. Hall Flavin Daniel, Matthew M. Clark, Victor M. Karpyak, Joseph D. Miller, Osama A. Abulseoud

Research output: Contribution to journalReview articlepeer-review

33 Scopus citations


The aim of this study is to describe the clinical phenotype of alcohol use disorder (AUD) treatment-seeking patients with Roux-en-Y Gastric Bypass Surgery (RYGB) history; and to compare it to AUD obese non-RYGB controls. Methods: Retrospective study of electronic medical records for all patients 30-60. years treated at the Mayo Clinic Addiction Treatment Program, between June, 2004 and July, 2012. Comparisons were performed with consumption patterns pre-RYGB and at time of treatment; excluding patients with AUD treatments pre-RYGB. Results: Forty-one out of 823 patients had a RYGB history (4.9%); 122 controls were selected. Compared to controls, the RYGB group had significantly more females [. n = 29 (70.7%) vs. n = 35 (28.7%) p < 0.0001]; and met AUD criteria at a significantly earlier age (19.1 ± 0.4 vs. 25.0 ± 1. years old, p = 0.002). On average, RYGB patients reported resuming alcohol consumption 1.4 ± 0.2. years post-surgery, meeting criteria for AUD at 3.1 ± 0.5. years and seeking treatment at 5.4 ± 0.3. years postoperatively. Pre-surgical drinks per day were significantly fewer compared to post-surgical consumption [2.5 ± 0.4 vs. 8.1 ± 1.3, p = 0.009]. Prior to admission, RYGB patients reported fewer drinking days per week vs. controls (4.7 ± 0.3 vs. 5.5 ± 1.8. days, p = 0.02). Neither RYGB, gender, age nor BMI was associated with differential drinking patterns. Conclusion: The results of this study suggest that some patients develop progressive AUD several years following RYGB. This observation has important clinical implications, calling for AUD-preventive measures following RYGB. Further large-scale longitudinal studies are needed to clarify the association between RYGB and AUD onset.

Original languageEnglish (US)
Pages (from-to)199-204
Number of pages6
JournalJournal of Psychosomatic Research
Issue number3
StatePublished - Mar 1 2015


  • Alcohol use disorder
  • Bariatric surgery
  • Relapse
  • Roux-en-Y gastric bypass (RYGB)

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health


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