Projects per year
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Collaborations and top research areas from the last five years
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Genomics of Alcohol Withdrawal and Treatment Response to Benzodiazepines
Karpyak, V. M. (PI) & Biernacka, J. M. (CoPI)
National Institute on Alcohol Abuse and Alcoholism
5/1/23 → 4/30/25
Project: Research project
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Integrated Therapies for Alcohol use in Alcohol-associated Liver Disease (ITAALD) – Mayo Clinic
Shah, V. V. H. (PI), Kamath, P. S. (CoPI) & Karpyak, V. M. (CoPI)
National Institute on Alcohol Abuse and Alcoholism
8/1/18 → 6/30/25
Project: Research project
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IMPACT OF SEX-RELATED HORMONE LEVELS AND GENETIC VARIATION ON ALCOHOL USE DISORDERS AND RELATED PHENOTYPES IN MALES AND FEMALES
Winham, S. J. (PI) & Karpyak, V. M. (CoPI)
National Institute on Alcohol Abuse and Alcoholism
9/20/19 → 8/31/21
Project: Research project
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Pharmacogenomics of Acamprosate Treatment Outcome (Supplement)
Karpyak, V. M. (PI) & Biernacka, J. M. (CoPI)
National Institute on Alcohol Abuse and Alcoholism
9/1/18 → 8/31/23
Project: Research project
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Pharmacogenomics of Treatment Outcomes in Alcohol Use Disorders
Biernacka, J. M. (PI) & Karpyak, V. M. (CoPI)
National Institute on Alcohol Abuse and Alcoholism
7/15/16 → 3/31/19
Project: Research project
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DNA methylation at DLGAP2 and risk for relapse in alcohol dependence during acamprosate treatment
Özel, F., Di Criscio, M., Lupu, D. I., Sarkisyan, D., Hlady, R. A., Robertson, K. D., Bakalkin, G., Liu, Y., Biernacka, J. M., Karpyak, V. M., Ekström, T. J. & Rüegg, J., Mar 1 2024, In: Drug and Alcohol Dependence. 256, 111116.Research output: Contribution to journal › Article › peer-review
Open Access -
IL17RB genetic variants are associated with acamprosate treatment response in patients with alcohol use disorder: A proteomics-informed genomics study
Ho, M. F., Zhang, C., Cohan, J. S., Tuncturk, M., Heider, R. M., Coombes, B. J., Biernacka, J., Moon, I., Skime, M., Ho, A. M., Ngo, Q., Skillon, C., Croarkin, P. E., Oesterle, T. S., Karpyak, V. M., Li, H. & Weinshilboum, R. M., Aug 2024, In: Brain, Behavior, and Immunity. 120, p. 304-314 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular mechanisms involved in alcohol craving, IRF3, and endoplasmic reticulum stress: a multi-omics study
Ho, M. F., Zhang, C., Moon, I., Tuncturk, M., Coombes, B. J., Biernacka, J., Skime, M., Oesterle, T. S., Karpyak, V. M., Li, H. & Weinshilboum, R., Dec 2024, In: Translational psychiatry. 14, 1, 165.Research output: Contribution to journal › Article › peer-review
Open Access -
Single cell transcriptomics reveals distinct transcriptional responses to oxycodone and buprenorphine by iPSC-derived brain organoids from patients with opioid use disorder
Ho, M. F., Zhang, C., Moon, I., Zhu, X., Coombes, B. J., Biernacka, J., Skime, M., Oesterle, T. S., Karpyak, V. M., Schmidt, K., Gliske, K., Ngo, Q., Skillon, C., Seppala, M. D., Li, H. & Weinshilboum, R. M., Jun 2024, In: Molecular Psychiatry. 29, 6, p. 1636-1646 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Systematic review and meta-analysis: Combining transcranial magnetic stimulation or direct current stimulation with pharmacotherapy for treatment of substance use disorders
Bormann, N. L., Oesterle, T. S., Arndt, S., Karpyak, V. M. & Croarkin, P. E., May 2024, In: American Journal on Addictions. 33, 3, p. 269-282 14 p.Research output: Contribution to journal › Review article › peer-review