Allergen immunotherapy

Matthew A. Rank, James T.C. Li

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


Allergen immunotherapy involves exposing a patient to a gradually escalating dose of a specific allergen with the intention of decreasing allergic and inflammatory responses, ultimately leading to a sustained decrease in allergic symptoms. A build-up phase (once weekly injections) is followed by a maintenance phase (once monthly injections) that generally continues for 3 to 5 years. Allergen immunotherapy is indicated for select patients with allergic rhinoconjunctivitis, allergic asthma, and stinging insect hypersensitivity. The safety and efficacy of allergen immunotherapy have been confirmed by numerous well-designed studies. Recent research has helped uncover the mechanisms by which allergen immunotherapy exerts its therapeutic effect, paving the way for the development of safer, more effective therapy for a wider range of allergic diseases.

Original languageEnglish (US)
Pages (from-to)1119-1123
Number of pages5
JournalMayo Clinic proceedings
Issue number9
StatePublished - Sep 2007

ASJC Scopus subject areas

  • General Medicine


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