Exosome pathway as a novel therapeutic target of tauopathy

Tau protein plays an important role in the development of Alzheimer’s and other neurodegenerative diseases, collectively known as “taupathies.” Tau normally functions to help maintain cell structure but in some brain diseases, it becomes abnormally modified, and can ultimately accumulate to form neurofibrillary tangles, a hallmark feature of Alzheimer’s disease and other taupathies.