Projects per year
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Dive into the research topics where Tsuneya Ikezu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Tumor susceptibility gene 101, a new microglial therapy candidate for Alzheimer’s disease to prevent cognitive decline
9/1/23 → 8/31/26
Project: Research project
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Molecular characterization of extracellular vesicles for the spread of misfolded tau protein
5/15/21 → 4/30/24
Project: Research project
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Targeting emerging P2RX7 signaling pathways in animal models of Alzheimer's disease
2/1/20 → 2/29/24
Project: Research project
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APOE and microglia-mediated progression in tau pathology in AD
9/30/16 → 8/31/24
Project: Research project
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Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice
Yukawa, K., Yamamoto-Mcguire, S., Cafaro, L., Hong, C., Kamme, F., Ikezu, T. & Ikezu, S., Dec 2023, In: Acta Neuropathologica Communications. 11, 1, 166.Research output: Contribution to journal › Article › peer-review
Open Access -
Comprehensive characterization of human brain-derived extracellular vesicles using multiple isolation methods: Implications for diagnostic and therapeutic applications
Zhang, Z., Yu, K., You, Y., Jiang, P., Wu, Z., DeTure, M. A., Dickson, D. W., Ikezu, S., Peng, J. & Ikezu, T., Aug 2023, In: Journal of Extracellular Vesicles. 12, 8, 12358.Research output: Contribution to journal › Article › peer-review
Open Access -
Extracellular vesicles as personalized medicine
Beetler, D. J., Di Florio, D. N., Bruno, K. A., Ikezu, T., March, K. L., Cooper, L. T., Wolfram, J. & Fairweather, D. L., Jun 2023, In: Molecular Aspects of Medicine. 91, 101155.Research output: Contribution to journal › Review article › peer-review
Open Access -
Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer’s disease
Yin, Z., Herron, S., Silveira, S., Kleemann, K., Gauthier, C., Mallah, D., Cheng, Y., Margeta, M. A., Pitts, K. M., Barry, J. L., Subramanian, A., Shorey, H., Brandao, W., Durao, A., Delpech, J. C., Madore, C., Jedrychowski, M., Ajay, A. K., Murugaiyan, G., Hersh, S. W., & 3 others, Jul 2023, In: Nature Neuroscience. 26, 7, p. 1196-1207 12 p.Research output: Contribution to journal › Article › peer-review
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INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model
Iguchi, A., Takatori, S., Kimura, S., Muneto, H., Wang, K., Etani, H., Ito, G., Sato, H., Hori, Y., Sasaki, J., Saito, T., Saido, T. C., Ikezu, T., Takai, T., Sasaki, T. & Tomita, T., Apr 21 2023, In: iScience. 26, 4, 106375.Research output: Contribution to journal › Article › peer-review
Open Access