Projects per year
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Collaborations and top research areas from the last five years
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Development of tools for site-directed analysis of gene function
Mcgrail, M. A., Friedberg, I., Essner, J. J., Clark, K. J. & Ekker, S. C.
6/1/16 → 2/29/24
Project: Research project
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Mayo Center for Cell Signaling in Gastroenterology
Larusso, N. N. F., Boardman, L. A., Ekker, S. C., Ekker, S. C., Farrugia, G., Faubion, W. A., Gores, G. J., La Russo, N. F., Mc Niven, M. A., Mc Niven, M. A., Shah, V., Ibrahim, S. H. & Ordog, T.
National Institute of Diabetes and Digestive and Kidney Diseases
9/1/09 → 6/30/24
Project: Research project
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Building the mitochondrial genome editing repertoire
National Institute of Allergy and Infectious Diseases
8/21/18 → 7/31/23
Project: Research project
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International Zebrafish Mutagenic Protein Trap
National Human Genome Research Institute
8/1/11 → 4/30/15
Project: Research project
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Mitochondrial Base Editing: Recent Advances towards Therapeutic Opportunities
Kar, B., Castillo, S. R., Sabharwal, A., Clark, K. J. & Ekker, S. C., Mar 2023, In: International journal of molecular sciences. 24, 6, 5798.Research output: Contribution to journal › Review article › peer-review
Open Access -
An optimized FusX assembly-based technique to introduce mitochondrial TC-to-TT variations in human cell lines
Kar, B., Sabharwal, A., Restrepo-Castillo, S., Simone, B. W., Clark, K. J. & Ekker, S. C., Jun 17 2022, In: STAR Protocols. 3, 2, 101288.Research output: Contribution to journal › Article › peer-review
Open Access -
A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene
Ding, Y., Lang, D., Yan, J., Bu, H., Li, H., Jiao, K., Yang, J., Ni, H., Morotti, S., Le, T., Clark, K. J., Port, J., Ekker, S. C., Cao, H., Zhang, Y., Wang, J., Grandi, E., Li, Z., Shi, Y., Li, Y., & 2 others , 2022, In: eLife. 11, e77327.Research output: Contribution to journal › Article › peer-review
Open Access -
A Primer Genetic Toolkit for Exploring Mitochondrial Biology and Disease Using Zebrafish
Sabharwal, A., Campbell, J. M., Schwab, T. L., WareJoncas, Z., Wishman, M. D., Ata, H., Liu, W., Ichino, N., Hunter, D. E., Bergren, J. D., Urban, M. D., Urban, R. M., Holmberg, S. R., Kar, B., Cook, A., Ding, Y., Xu, X., Clark, K. J. & Ekker, S. C., Aug 2022, In: Genes. 13, 8, 1317.Research output: Contribution to journal › Article › peer-review
Open Access -
Chimeric RNA: DNA TracrRNA Improves Homology-Directed Repair in Vitro and in Vivo
Simone, B. W., Lee, H. B., Daby, C. L., Ata, H., Restrepo-Castillo, S., Martínez-Gálvez, G., Kar, B., Gendron, W. A. C., Clark, K. J. & Ekker, S. C., Feb 2022, In: CRISPR Journal. 5, 1, p. 40-52 13 p.Research output: Contribution to journal › Article › peer-review
Open Access