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Dive into the research topics where Arun Kanakkanthara is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
- 2 Active
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NAD+ metabolism in PARP inhibitor resistance of ovarian cancer
6/15/21 → 5/31/24
Project: Research project
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Exploiting a Metabolic Dependency of PARPinhibitor-Resistant Ovarian Cancer
Ovarian Cancer Research Alliance
1/1/21 → 12/31/23
Project: Research project
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Repurposing Ceritinib Induces DNA Damage and Enhances PARP Inhibitor Responses in High-Grade Serous Ovarian Carcinoma
Kanakkanthara, A., Hou, X., Ekstrom, T. L., Zanfagnin, V., Huehls, A. M., Kelly, R. L., Ding, H., Larson, M. C., Vasmatzis, G., Oberg, A. L., Kaufmann, S. H., Mansfield, A. S., Weroha, S. J. & Karnitz, L. M., Jan 15 2022, In: Cancer research. 82, 2, p. 307-319 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
VLX600 disrupts homologous recombination and synergizes with PARP inhibitors and cisplatin by inhibiting histone lysine demethylases
Ekstrom, T. L., Pathoulas, N. M., Huehls, A. M., Kanakkanthara, A. & Karnitz, L. M., Sep 2021, In: Molecular cancer therapeutics. 20, 9, p. 1561-1571 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
βIII-tubulin overexpression in cancer: Causes, consequences, and potential therapies
Kanakkanthara, A. & Miller, J. H., Dec 2021, In: Biochimica et Biophysica Acta - Reviews on Cancer. 1876, 2, 188607.Research output: Contribution to journal › Review article › peer-review
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Beyond the paclitaxel and vinca alkaloids: Next generation of plant-derived microtubule-targeting agents with potential anticancer activity
Zhang, D. & Kanakkanthara, A., Jul 2020, In: Cancers. 12, 7, p. 1-23 23 p., 1721.Research output: Contribution to journal › Review article › peer-review
Open Access6 Scopus citations -
BRCA1 deficiency upregulates NNMT, which reprograms metabolism and sensitizes ovarian cancer cells to mitochondrial metabolic targeting agents
Kanakkanthara, A., Kurmi, K., Ekstrom, T. L., Hou, X., Purfeerst, E. R., Heinzen, E. P., Correia, C., Huntoon, C. J., O'Brien, D., Wahner Hendrickson, A. E., Dowdy, S. C., Li, H., Oberg, A. L., Hitosugi, T., Kaufmann, S. H., Weroha, S. J. & Karnitz, L. M., Dec 1 2019, In: Cancer research. 79, 23, p. 5920-5929 10 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations