General Internal Medicine

Projects

Projects per year 1997 2009 2012 2015 2016 2018 2019 2020 2025

• 7 Active
• 20 Finished

Projects per year

Search results

• Active

  MRI-based quantitative characterization of impaired myofascial interface properties in myofascial pain syndrome

  Yin, Z. Z. & Bauer, B. A.

  National Center for Complementary and Integrative Health

  9/19/22 → 8/31/25

  Project: Research project

  • Myofascial Pain Syndromes 100%
  • Biomarkers 73%
  • Pain 43%
  • Fascia 42%
  • Biomechanical Phenomena 36%

• Density MATTERS Clinical Trial

  Hruska, C. B. & Rhodes, D.

  National Cancer Institute

  9/1/20 → 5/31/24

  Project: Research project

  • Breast 100%
  • Mammography 98%
  • Molecular Imaging 82%
  • Clinical Trials 60%
  • Breast Neoplasms 24%

• ALSENLITE: An Open-Label Pilot Study Of Senolytics For Alzheimer Disease

  Kirkland, J. L.

  Alzheimer’s Association

  1/1/20 → …

  Project: Research project

  • Alzheimer Disease 100%
  • Research Personnel 77%
  • Pharmaceutical Preparations 76%
  • Clinical Trials 59%
  • Brain 54%

• Targeting Cellular Senescence to Extend Healthspan

  Khosla, S. S., Ikeno, Y., Kirkland, J. L., LeBrasseur, N. K., Pignolo, R. J. & Robbins, P. D.

  National Institute on Aging

  6/1/19 → 1/31/24

  Project: Research project

  • Biostatistics 21%
  • Nexus 19%
  • Blood Vessels 16%
  • Frailty 16%
  • Extracellular Matrix Proteins 15%

• Metabolic Dysfunction

  Kirkland, J. L. & Kirkland, J. L.

  National Institute on Aging

  4/15/19 → 1/31/24

  Project: Research project

  • Adipose Tissue 50%
  • Obese Mice 12%
  • Physiological Stress 12%
  • Cardiovascular System 9%
  • Adipocytes 9%

• Translational Geroscience Network

  Kirkland, J. L., Kritchevsky, S. B., Kuchel, G. A. & Tchkonia, T.

  National Institute on Aging

  2/1/19 → 11/30/23

  Project: Research project

  • Proteostasis 100%
  • Idiopathic Pulmonary Fibrosis 92%
  • Organized Financing 90%
  • Manuals 88%
  • Frailty 87%

• INK-ER-Cre mice: a novel tool for uncovering how senescent cells cause age-related dysfunction

  Kirkland, J. L.

  American Federation for Aging Research

  1/1/12 → …

  Project: Research project

  • Inflammation 100%
  • Muscle Strength 86%
  • Cataract 79%
  • Dementia 71%
  • Atherosclerosis 68%
• Finished

  Sen-Survivors: An open-label intervention trial for frailty and senescence

  Armstrong, G. & Kirkland, J. L.

  National Cancer Institute

  9/1/20 → 8/31/23

  Project: Research project

  • Frailty 100%
  • Survivors 63%
  • Walking Speed 47%
  • fisetin 33%
  • Dasatinib 28%

• Senescence cells as a source of pro-aging miR-146a

  Masternak, M. M. & Kirkland, J. L.

  National Institute on Aging

  9/1/19 → 8/31/20

  Project: Research project

  • MicroRNAs 100%
  • TNF Receptor-Associated Factor 6 43%
  • Longevity 26%
  • Insulin Resistance 24%
  • Insulin 20%

• Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease

  Kantarci, K. M., Kapoor, E., LeBrasseur, N. K., Miller, V. M., Morrow, M. M. & Mielke, M. M.

  National Institute on Aging

  9/30/18 → 5/31/23

  Project: Research project

  • dementia 100%
  • leadership 29%
  • menopause 19%
  • career 19%
  • work force 17%

• Resource Support Core - Clinical

  Kapoor, E. & Kapoor, E. E.

  National Institute on Aging

  9/30/18 → 5/31/23

  Project: Research project

  • Salpingo-oophorectomy 100%
  • Medical Record Linkage 44%
  • Cohort Studies 35%
  • Data Management 34%
  • Databases 31%

• Systems Biology of Mumps Vaccine Response

  Kennedy, R. B.

  National Institute of Allergy and Infectious Diseases

  6/15/18 → 5/31/23

  Project: Research project

  • Mumps Vaccine 100%
  • Mumps 78%
  • Systems Biology 72%
  • Immunity 37%
  • B-Lymphocytes 17%

• Transcriptomic Signatures of Influenza Vaccine Responses

  Poland, G. A. & Kennedy, R. B.

  National Institute of Allergy and Infectious Diseases

  1/17/18 → 12/31/22

  Project: Research project

  • Influenza Vaccines 100%
  • Helper-Inducer T-Lymphocytes 79%
  • MF59 oil emulsion 67%
  • Vaccines 57%
  • Human Influenza 48%

• Understanding measles vaccine failure (and success) in Southern India

  Kennedy, R. B. & Jacob, J.

  National Institute of Allergy and Infectious Diseases

  3/1/17 → 2/28/18

  Project: Research project

  • Measles Vaccine 100%
  • Measles 86%
  • India 62%
  • Vaccines 34%
  • Disease Outbreaks 33%

• Genetic Markers of Long-Term Mumps Vaccine Immunity

  Kennedy, R. B.

  National Institute of Allergy and Infectious Diseases

  9/21/16 → 8/31/21

  Project: Research project

  • Mumps Vaccine 100%
  • Genetic Markers 54%
  • Immunity 45%
  • Mumps 38%
  • Single Nucleotide Polymorphism 33%

• SCH: EXP: Collaborative Research: Group-Specific Learning to Personalize Evidence-Based Medicine

  Caraballo, P. & Shah, N. D.

  National Science Foundation

  9/1/16 → 8/31/21

  Project: Research project

  • Evidence-Based Medicine 100%
  • Precision Medicine 95%
  • Guidelines 93%
  • Multiple Chronic Conditions 71%
  • Learning 70%

• Effect of Aging on Preadipocyte Differentiation

  Kirkland, J. L.

  National Institute on Aging

  4/15/16 → 3/31/21

  Project: Research project

  • Phenotype 100%
  • Transgenic Suicide Genes 56%
  • Chronic Disease 40%
  • Pharmacology 36%
  • Frailty 31%

• Imaging for Cellular Senescence

  Kirkland, J. L. & Lowe, V.

  National Institute on Aging

  9/1/15 → 5/31/16

  Project: Research project

  • 2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole 67%
  • Electrons 45%
  • Protein Aggregates 36%
  • Luminescence 24%
  • Autopsy 12%

• Senescent Cell Transplantation Model

  Kirkland, J. L.

  8/15/15 → 5/31/16

  Project: Research project

  • AP20187 88%
  • Chronic Disease 50%
  • Cell Transplantation 49%
  • Glucose Intolerance 48%
  • Suicide 42%

• Cellular Senescence, the Senescent Secretory Phenotype and JAK

  Kirkland, J. L.

  National Institute on Aging

  5/1/12 → 4/30/17

  Project: Research project

  • Phenotype 34%
  • Fats 32%
  • Adipogenesis 31%
  • Inflammation 20%
  • Frailty 19%

• Administrative Core

  Kirkland, J. L.

  National Institute on Aging

  5/1/12 → 4/30/17

  Project: Research project

  • Advisory Committees 96%
  • Frailty 52%
  • Videoconferencing 32%
  • Annual Reports 31%
  • Translational Medical Research 25%

• Cellular Senescence and Aging

  Kirkland, J. L., Campisi, J., Van Deursen, J., LeBrasseur, N. K., Mooney, S. & Van Deursen, J.

  5/1/12 → 4/30/17

  Project: Research project

  • Frailty 40%
  • Inflammasomes 16%
  • Animal Models 10%
  • Systems Biology 8%
  • Biomedical Research 7%

• Dysfunctional regeneration in cardiomyopathy: iPS-based diagnosis and therapy

  Nelson, T. J.

  NIH Office of the Director

  9/30/10 → 6/30/15

  Project: Research project

  • Stem Cells 100%
  • Cardiomyopathies 88%
  • Regeneration 85%
  • Familial dilated cardiomyopathy 75%
  • Myocardium 56%

• IGF-I' S INFLUENCE ON PRE-ADIPOCYTES

  Kirkland, J. L.

  National Institute on Aging

  4/15/09 → 3/31/14

  Project: Research project

  • Insulin-Like Growth Factor I 100%
  • Fats 80%
  • Adipocytes 75%
  • Nexus 23%
  • Physiological Stress 19%

• The Somatotropic Axis and Health Aging: A Search for Mechanisms

  Bartke, A., Ikeno, Y., Kirkland, J. L., Kopchick, J. J. & Miller, R. A.

  4/15/09 → 3/31/15

  Project: Research project

  • somatotropin 100%
  • advisory committees 34%
  • insulin-like growth factor I 32%
  • insulin 26%
  • mice 26%

• Regional Differences in Preadipocyte Development

  Kirkland, J. L. & Kirkland, J. L.

  National Institute on Aging

  9/30/03 → 11/30/09

  Project: Research project

  • Fats 100%
  • Apoptosis 64%
  • Adipocytes 50%
  • Metabolic Syndrome 48%
  • Cyclic AMP Response Element-Binding Protein 33%

• Effect of Aging on Preadipocyte Differentiation

  Kirkland, J. L. & Kirkland, J. L.

  National Institute on Aging

  5/15/97 → 7/31/14

  Project: Research project

  • Fats 100%
  • Adipogenesis 57%
  • Physiological Stress 34%
  • Adipocytes 27%
  • Phenotype 22%