Vulvar glomangioma: A case report and literature review

Kyle E. Robinson, Ali D. Tahbouh Amawi, Sudhakar K. Venkatesh, Jorge Torres-Mora, Ellen West, Amanika Kumar

Research output: Contribution to journalArticlepeer-review


GLMN is a gene that encodes a critical protein necessary for normal vascular development. Mutations of GLMN predispose individuals to development of glomangiomas, with nearly 100% penetrance by age 30. Glomangiomas are tumors of the glomus body, a thermoregulatory arterial-venous shunt composed of modified smooth muscle cells. Vulvar glomangioma is an exceedingly rare cause of chronic pelvic pain, that may be easily confused for other conditions such as Bartholin's gland abscess or deep angiomxyomas, thereby delaying diagnosis and treatment. Glomangiomas have characteristic pathologic and imaging findings which may aid diagnosis. We herein describe the case of a 24-year-old female who developed chronic pelvic pain in the setting of a vulvar glomangioma. We further delineate the magnetic resonance imaging and biopsy findings critical to her diagnosis, and the appropriate steps taken for surgical management. She was found to harbor a heterozygous GLMN mutation. To the best of our knowledge, this is the first description of such a case in the medical literature.

Original languageEnglish (US)
Article number101034
JournalGynecologic Oncology Reports
StatePublished - Aug 2022


  • GLMN gene
  • Glomangioma
  • Vulvar neoplasm

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology


Dive into the research topics of 'Vulvar glomangioma: A case report and literature review'. Together they form a unique fingerprint.

Cite this