Vulvar Crohn's Disease: Clinical Features and Outcomes

Janice M. Cho, Edward V. Loftus, David H. Bruining, Victor G. Chedid, Francis A. Farraye, William A. Faubion, Amanda M. Johnson, Sunanda V. Kane, John B. Kisiel, Talha A. Malik, Konstantinos A. Papadakis, Darrell S. Pardi, Michael F. Picco, Laura E. Raffals, Kenneth W. Schroeder, William J. Tremaine, Nayantara Coelho-Prabhu

Research output: Contribution to journalArticlepeer-review


INTRODUCTION:Vulvar involvement is a rare complication of Crohn's disease (CD). The optimal treatment of vulvar CD is unknown.METHODS:We conducted a 25-year retrospective cohort study of vulvar CD from 3 referral centers. Clinical features and outcomes were studied.RESULTS:Fifty patients were identified. The most common vulvar symptoms were pain (74%), edema (60%), ulcerations (46%), nodules (36%), and abscess (34%). Medical management leading to symptomatic improvement varied, and 5 patients ultimately required surgery.DISCUSSION:Vulvar CD manifests with a broad spectrum of symptoms. Aggressive medical management was frequently effective, although surgery was required in 10% of cases.

Original languageEnglish (US)
Pages (from-to)2296-2299
Number of pages4
JournalAmerican Journal of Gastroenterology
Issue number11
StatePublished - Nov 1 2021

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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