Volume-outcome relationships for percutaneous coronary interventions in the stent era

Edward L. Hannan, Chuntao Wu, Gary Walford, Spencer B. King, David R. Holmes, John A. Ambrose, Samin Sharma, Stanley Katz, Luther T. Clark, Robert H. Jones

Research output: Contribution to journalArticlepeer-review

153 Scopus citations


Background - Most studies that are the basis of recommended volume thresholds for percutaneous coronary interventions (PCIs) predate the routine use of stent placement. Methods and Results - Data from New York's Percutaneous Coronary Interventions Reporting System in 1998 to 2000 (n=107 713) were used to examine the impact of annual hospital volume and annual operator volume on in-hospital mortality, same-day coronary artery bypass graft (CABG) surgery, and same- stay CABG surgery after adjustment for differences in patients' severity of illness. For a hospital-volume threshold of 400, the odds ratios for low-volume hospitals versus high-volume hospitals were 1.98 (95% CI, 1.17, 3.35) for in-hospital mortality, 2.07 (95% CI, 1.36, 3.15) for same-day CABG surgery, and 1.51 (95% CI, 1.03, 2.21) for same-stay CABG surgery. For an operator-volume threshold of 75, the odds ratios for low-volume versus high-volume operators were 1.65 (95% CI, 1.05, 2.60) for same-day CABG surgery and 1.55 (95% CI, 1.10, 2.18) for same-stay CABG surgery. Operator volume was not significantly associated with mortality. Also, for hospital volumes below 400 and operator volumes below 75, the respective odds of mortality, same-day CABG surgery, and same-stay CABG surgery were 5.92, 4.02, and 3.92 times the odds for hospital volumes of 400 or higher and operator volumes of 75 or higher. Conclusions - Higher-volume operators and hospitals continue to experience lower risk-adjusted PCI outcome rates.

Original languageEnglish (US)
Pages (from-to)1171-1179
Number of pages9
Issue number8
StatePublished - Aug 23 2005


  • Angioplasty
  • Coronary disease
  • Mortality
  • Revascularization
  • Stents

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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