V.I.T.A.M. in COVID 19: A Systematic Approach to a Global Pandemic

Siva Naga S. Yarrarapu, Pankaj Bansal, David Abia-Trujillo, Austin Cusick, Megan Melody, Varun Moktan, Andrea Rivero, Tara J. Brigham, Claudia Libertin, Lisa Brumble, J. O’brein Jennifer, Augustine Lee, Torp Klaus, Christan Santos, Candido Rivera, Jason Siegel, Pramod Guru, Pablo Moreno Franco, Devang Sanghavi

Research output: Contribution to journalArticlepeer-review


Introduction: In the unprecedented era of COVID-19, ongoing research and evolution of evidence has led to ever-changing guidelines for clinical monitoring and therapeutic options. Formulating treatment protocols requires the understanding and application of the evolving research. Objective: The primary objective of this study is to present a systematic evidence-based approach to synthesize the necessary data in order to optimize the management of COVID-19. Methods: At Mayo Clinic Florida, we developed a multidisciplinary centralized COVID Treatment Review Panel (TRP) of expert pulmonologists, intensivists, infectious disease specialists, anesthesiologists, hematologists, rheumatologists, and hospitalists that in real-time reviews the latest evidence in peer-reviewed journals, the available clinical trials, and help guide the rapid application of therapeutics or interventions to the patient and the bedside provider. Results/Conclusions: The multi-disciplinary team approach of synthesizing clinical data and coordinating care is effective in responding to rapidly evolving and changing evidence. Systematic data collection and evidence-based treatment algorithms enable physicians to rapidly translate the current literature to clinical practice, and improve care and outcomes of patients.


  • COVID-19
  • inflammatory
  • microbiological
  • oxygenation
  • thrombotic

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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