Viral and immune-mediated factors in the pathogenesis of psychiatric disease.

D. A. Drubach, H. S. Panitch, K. P. Johnson

Research output: Contribution to journalReview articlepeer-review


The available data supporting a viral or immune mediated etiology of psychiatric disease is indirect and controversial, but there is a sufficient evidence to implicate such a process in a subgroup of the psychiatric population. Recent technological advances in neurovirology and neuroimmunology justify a re-assessment of this etiology in psychiatric disease. The author describes three patients with psychiatric symptomatolgy and cerebrospinal changes compatible with such a process. The evidence supporting a role for viral or immunological factors in the pathogenesis of psychiatric disease is reviewed, and guidelines for future research which could be of use in further clarifying this issue are proposed.

Original languageEnglish (US)
Pages (from-to)163-183
Number of pages21
JournalThe Hillside journal of clinical psychiatry
Issue number2
StatePublished - 1987

ASJC Scopus subject areas

  • Psychiatry and Mental health


Dive into the research topics of 'Viral and immune-mediated factors in the pathogenesis of psychiatric disease.'. Together they form a unique fingerprint.

Cite this