Abstract
Abnormalities in vascular stiffness and their coupling with ventricular systolic and diastolic performance contribute to exercise intolerance and symptom manifestation in heart failure with preserved ejection fraction (HFpEF). In this chapter, we will discuss the physiology of normal and abnormal ventricular-vascular coupling and how it relates to HFpEF.
Original language | English (US) |
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Title of host publication | Diastology |
Subtitle of host publication | Clinical Approach to Heart Failure with Preserved Ejection Fraction |
Publisher | Elsevier |
Pages | 71-85 |
Number of pages | 15 |
ISBN (Electronic) | 9780323640671 |
DOIs | |
State | Published - Jan 1 2020 |
Keywords
- Afterload
- Effective arterial elastance
- End-systolic elastance
- Exercise capacity
- Heart failure with preserved ejection fraction
- Pulsatile load
- Vascular stiffness
ASJC Scopus subject areas
- Medicine(all)