Vascular Diseases of the Liver

Moira B. Hilscher, Patrick S. Kamath

Research output: Chapter in Book/Report/Conference proceedingChapter


The Budd–Chairi syndrome (BCS) is a consequence of hepatic venous outflow obstruction at the hepatic venules, major hepatic veins, or inferior vena cava. The prevalence and etiology of BCS demonstrates significant geographic heterogeneity. The clinical manifestations of BCS are similarly variable and depend on the extent and acuity of obstruction. Medical management of BCS relies on identification of the precipitating factor, anticoagulation to prevent propagation of the obstruction, and sodium restriction and diuretics to manage ascites. In select cases, hepatic venous outflow obstruction can be relieved through the use of thrombolytics, angioplasty, and stenting, or transjugular intrahepatic portosystemic shunting (TIPS).

Original languageEnglish (US)
Title of host publicationEncyclopedia of Gastroenterology, Second Edition
Number of pages7
ISBN (Electronic)9780128124604
StatePublished - Jan 1 2019


  • Angioplasty
  • Ascites
  • Hepatic vein
  • Inferior vena cava
  • Liver transplantation
  • Polycythemia vera
  • Thrombosis
  • Transjugular intrahepatic portosystemic shunt

ASJC Scopus subject areas

  • General Medicine


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