Valvular heart disease in patients with osteogenesis imperfecta

Mohammad Q. Najib, Hartzell V. Schaff, Jhansi Ganji, Howard R. Lee, Roger L. Click, D. Craig Miller, Hari P. Chaliki

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Osteogenesis imperfecta (OI) or "brittle bone disease" is a rare connective tissue hereditary disorder. The most common clinical presentation of OI is bone fractures. OI also involves extraskeletal structures; however, cardiovascular manifestations are rare. In this report, we describe the cardiovascular anomalies of patients with OI who underwent valve surgery and review the literature on this subject.

Original languageEnglish (US)
Pages (from-to)139-143
Number of pages5
JournalJournal of cardiac surgery
Issue number2
StatePublished - Mar 2013

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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