Valve morphology in antiphospholipid antibody syndrome: Echocardiographic features

Fatema Qaddoura, Heidi Connolly, Martha Grogan, Tom A. Orszulak, Hartzell V. Schaff, Krishnaswamy Chandrasekaran, Roger L. Click

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Primary antiphospholipid antibody (PAP) syndrome can present with a variety of clinical manifestations including cardiac valvular lesions. Prior reports of the valvular lesions associated with PAP have been nonspecific. The purpose of this paper is to present four cases of patients with documented PAP and demonstrate the characteristic transesophageal echocardiographic features. The primary feature is focal, symmetrical, nodular thickening at the leaflet's coaptation points.

Original languageEnglish (US)
Pages (from-to)255-259
Number of pages5
Issue number3
StatePublished - Mar 1 2005


  • Antiphospholipid syndrome
  • Aortic valve
  • Mitral valve
  • Nonthrombotic vegetation
  • Transesophageal echocardiography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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