Value-Based Care in Hematopoietic Cell Transplantation and Cellular Therapy: Challenges and Opportunities

Gunjan L. Shah, Navneet Majhail, Nandita Khera, Sergio Giralt

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


Purpose of Review: Improved tolerability and outcomes after hematopoietic cell transplantation (HCT), along with the availability of alternative donors, have expanded its use. With this growth, and the development of additional cellular therapies, we also aim to increase effectiveness, efficiency, and the quality of the care provided. Fundamentally, the goal of value-based care is to have better health outcomes with streamlined processes, improved patient experience, and lower costs for both the patients and the health care system. HCT and cellular therapy treatments are multiphase treatments which allow for interventions at each juncture. Recent Findings: We present a summary of the current literature with focus on program structure and overall system capacity, coordination of therapy across providers, standardization across institutions, diversity and disparities in care, patient quality of life, and cost implications. Summary: Each of these topics provides challenges and opportunities to improve value-based care for HCT and cellular therapy patients.

Original languageEnglish (US)
Pages (from-to)125-134
Number of pages10
JournalCurrent Hematologic Malignancy Reports
Issue number2
StatePublished - Apr 1 2018


  • CAR-T cell
  • Cellular therapy
  • Hematopoietic cell transplantation
  • Value-base care

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research


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