Valproate-induced fanconi syndrome in a 27-year-old woman

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10 Scopus citations


Valproate-induced Fanconi Syndrome (VFS) is a rare complication of this therapy that has been previously described only in children with epilepsy. We report the first known case of an adult with VFS. Metabolic derangements lead patients to present with fatigue, confusion, weakness, and even bone fractures. Identification and discontinuation of the offending agent is the treatment of choice and helps confirm the diagnosis. This case highlights the importance of surveillance for metabolic derangements among patients on long term therapy with this commonly prescribed medication.

Original languageEnglish (US)
Pages (from-to)1072-1074
Number of pages3
JournalJournal of general internal medicine
Issue number9
StatePublished - Sep 2011


  • Fanconi syndrome
  • adult
  • valproate
  • valproic acid

ASJC Scopus subject areas

  • Internal Medicine


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