Uveal melanoma extension to the optic chiasm

Amro Abdellatief, Jose S Pulido, George B. Bartley, Diva R. Salomao, Timothy A. Quinn

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Purpose: Case report describing a patient who developed intracranial extension of a uveal melanoma through the optic nerve. Methods: We reviewed the patient's medical history and images. A 41-year-old woman who was blind in one eye had a uveal melanoma that extended through the optic nerve into the optic chiasm and involved the hypophysis. The patient then developed metastasis. Results: The patient developed uveal melanoma extension into the optic chiasm through the optic nerve resulting in a visual field defect in the fellow eye. Conclusion: Uveal melanoma extension through the optic nerve is a devastating complication, which occurs anywhere from 0.6% to 3.7% in patients with uveal melanoma. If enucleation of the affected eye is performed, a representative portion of the optic nerve should be excised to decrease the risk of extension. Patients with phthisical eyes should undergo appropriate imaging techniques to prevent a missed diagnosis of optic nerve involvement.

Original languageEnglish (US)
Pages (from-to)1-5
Number of pages5
JournalRetinal Cases and Brief Reports
Issue number1
StatePublished - Jan 1 2016


  • Extrascleral
  • Malignant melanoma
  • Optic chiasm
  • Optic nerve
  • Phthisical eye
  • Uveal melanoma

ASJC Scopus subject areas

  • Ophthalmology


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