TY - JOUR
T1 - Update on Influenza Vaccines
T2 - Needs and Progress
AU - Kennedy, Richard B.
AU - Ovsyannikova, Inna G.
AU - Poland, Gregory A.
N1 - Publisher Copyright:
© 2021
PY - 2021/10
Y1 - 2021/10
N2 - Influenza is an annual seasonal epidemic, and occasionally pandemic, respiratory disease that causes considerable morbidity and mortality worldwide. Despite the widespread availability of safe and effective vaccines since the 1950s, this virus continues to pose a significant public health threat. Variable and often weak vaccine effectiveness, antigenic drift and shift, and vaccine hesitancy are some of the obstacles that must be overcome to control this disease. In this article, we briefly review current influenza vaccines, address safety concerns and the need for newer influenza vaccines of higher efficacy, and discuss efforts to create broadly protective, universal influenza vaccines.
AB - Influenza is an annual seasonal epidemic, and occasionally pandemic, respiratory disease that causes considerable morbidity and mortality worldwide. Despite the widespread availability of safe and effective vaccines since the 1950s, this virus continues to pose a significant public health threat. Variable and often weak vaccine effectiveness, antigenic drift and shift, and vaccine hesitancy are some of the obstacles that must be overcome to control this disease. In this article, we briefly review current influenza vaccines, address safety concerns and the need for newer influenza vaccines of higher efficacy, and discuss efforts to create broadly protective, universal influenza vaccines.
KW - Epidemic
KW - Influenza
KW - Influenza vaccines
KW - Pandemic
KW - Respiratory disease
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U2 - 10.1016/j.jaip.2021.08.003
DO - 10.1016/j.jaip.2021.08.003
M3 - Article
C2 - 34416408
AN - SCOPUS:85114301800
SN - 2213-2198
VL - 9
SP - 3599
EP - 3603
JO - Journal of Allergy and Clinical Immunology: In Practice
JF - Journal of Allergy and Clinical Immunology: In Practice
IS - 10
ER -