Ultrasound vibrometry using orthogonal-frequency-based vibration pulses

Yi Zheng, Aiping Yao, Shigao Chen, Matthew W. Urban, Haoming Lin, Xin Chen, Yanrong Guo, Ke Chen, Tianfu Wang, Siping Chen

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


New vibration pulses are developed for shear wave generation in a tissue region with preferred spectral distributions for ultrasound vibrometry applications. The primary objective of this work is to increase the frequency range of detectable harmonics of the shear wave. The secondary objective is to reduce the required peak intensity of transmitted pulses that induce the vibrations and shear waves. Unlike the periodic binary vibration pulses, the new vibration pulses have multiple pulses in one fundamental period of the vibration. The pulses are generated from an orthogonal-frequency wave composed of several sinusoidal signals, the amplitudes of which increase with frequency to compensate for higher loss at higher frequency in tissues. The new method has been evaluated by studying the shear wave propagation in in vitro chicken and swine liver. The experimental results show that the new vibration pulses significantly increase tissue vibration with a reduced peak ultrasound intensity, compared with the binary vibration pulses.

Original languageEnglish (US)
Article number6644739
Pages (from-to)2359-2370
Number of pages12
JournalIEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Issue number11
StatePublished - 2013

ASJC Scopus subject areas

  • Instrumentation
  • Acoustics and Ultrasonics
  • Electrical and Electronic Engineering


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