Tumefactive cerebral amyloid angiopathy mimicking CNS neoplasm

Amy L. Kotsenas, Jonathan M. Morris, John T. Wald, Joseph E. Parisi, Norbert G. Campeau

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


OBJECTIVE. The tumefactive variant of cerebral amyloid angiopathy (CAA) is rare. In this article we describe imaging findings associated with this entity and evaluate the role of susceptibility MRI sequences in its diagnosis. CONCLUSION. Our findings suggest that in elderly patients, susceptibility sequences should be part of prebiopsy MRI for tumefactive lesions. Identification of characteristic diffuse microhemorrhages should prompt inclusion of CAA in the differential diagnosis, targeted biopsy of the cortex and leptomeninges, and pathologic staining for CAA.

Original languageEnglish (US)
Pages (from-to)50-56
Number of pages7
JournalAmerican Journal of Roentgenology
Issue number1
StatePublished - Jan 2013


  • CNS
  • Cerebral amyloid angiopathy
  • Microhemorrhage
  • Neoplasm
  • Superficial hemosiderosis
  • Susceptibility MRI sequences

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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