Trisomy 5 in Ph+ chronic myeloid leukemia in association with megakaryocytosis

Stephen M. Ansell, Bernardo L. Rapoport, Maria A. Coccia-Portugal, Kenneth Stevens, Catharina J. Bester, Geoffrey Falkson

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


A patient with a megakaryocytosis associated with a Philadelphia chromosome-positive chronic myeloid leukemia (CML) was found to have a trisomy of chromosome five. To our knowledge, this is the first case of trisomy 5 associated with a Ph+ CML, particularly one with a megakaryocytosis. The trisomy 5 may be associated with the resistance to cytostatic drugs found in this patient.

Original languageEnglish (US)
Pages (from-to)273-275
Number of pages3
JournalCancer Genetics and Cytogenetics
Issue number2
StatePublished - Feb 1991

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research


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