Abstract
What is this summary about? This is a summary of three articles describing preventive treatment of migraine in participants with a diagnosis of both chronic migraine and medication-overuse headache in a study called PROMISE-2 (PRevention Of Migraine via Intravenous ALD403 Safety and Efficacy-2). People living with chronic migraine and medication-overuse headache have one of the most disabling, costly, and difficult-to-treat headache disorders. What were the results? After preventive migraine treatment with eptinezumab (trade name Vyepti), participants with chronic migraine and medication-overuse headache experienced fewer migraine days, a reduced severity of migraine attacks, and a reduced use of acute medication. More participants receiving eptinezumab treatment no longer met the definition of either chronic migraine or medication-overuse headache throughout the study when compared with those receiving placebo. What do the results mean? Eptinezumab is beneficial for people who often use acute medication(s) due to frequent headache episodes or migraine attacks. </sec.
Original language | English (US) |
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Pages (from-to) | 317-327 |
Number of pages | 11 |
Journal | Pain Management |
Volume | 13 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1 2023 |
Keywords
- Acute medication
- Headache
- Migraine
- lay summary
- medication-overuse headache
- plain language summary
- preventive treatment
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine