Treatment of reflex sympathetic dystrophy with topical capsaicin. Case report

William P. Cheshire; Clyde R. Snyder

doi:10.1016/0304-3959(90)91143-7

Treatment of reflex sympathetic dystrophy with topical capsaicin. Case report

William P. Cheshire, Clyde R. Snyder

Neurology

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

A 31-year-old woman with intractable reflex sympathetic dystrophy experienced nearly complete, though temporary, resolution of pain following 3 weeks of topical capsaicin. We propose that capsaicin may be a useful treatment for reflex sympathetic dystrophy, either by depleting substance P from primary afferent neurons that mediate allodynia, or by modulating sympathetic efferent activity.

Original language	English (US)
Pages (from-to)	307-311
Number of pages	5
Journal	Pain
Volume	42
Issue number	3
DOIs	https://doi.org/10.1016/0304-3959(90)91143-7
State	Published - Sep 1990

Keywords

Allodynia
Capsaicin
Reflex sympathetic dystrophy
Substance P

ASJC Scopus subject areas

Neurology
Clinical Neurology
Anesthesiology and Pain Medicine

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10.1016/0304-3959(90)91143-7

Cite this

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title = "Treatment of reflex sympathetic dystrophy with topical capsaicin. Case report",

abstract = "A 31-year-old woman with intractable reflex sympathetic dystrophy experienced nearly complete, though temporary, resolution of pain following 3 weeks of topical capsaicin. We propose that capsaicin may be a useful treatment for reflex sympathetic dystrophy, either by depleting substance P from primary afferent neurons that mediate allodynia, or by modulating sympathetic efferent activity.",

keywords = "Allodynia, Capsaicin, Reflex sympathetic dystrophy, Substance P",

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AU - Snyder, Clyde R.

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AB - A 31-year-old woman with intractable reflex sympathetic dystrophy experienced nearly complete, though temporary, resolution of pain following 3 weeks of topical capsaicin. We propose that capsaicin may be a useful treatment for reflex sympathetic dystrophy, either by depleting substance P from primary afferent neurons that mediate allodynia, or by modulating sympathetic efferent activity.

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KW - Capsaicin

KW - Reflex sympathetic dystrophy

KW - Substance P

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ER -

Treatment of reflex sympathetic dystrophy with topical capsaicin. Case report

Abstract

Keywords

ASJC Scopus subject areas

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