Treatment of giant cell tumors of the distal radius: A long-term patient-reported outcomes study

Doga Kuruoglu, Marco Rizzo, Peter S. Rose, Steven L. Moran, Matthew T. Houdek

Research output: Contribution to journalArticlepeer-review


Introduction: The distal radius is a common location for giant cell tumors (GCTs) of bone. Management includes intralesional curettage or wide excision, however, long-term comparisons of treatment options are limited. The purpose of the current study was to evaluate our institutions' outcomes of treatment of these tumors. Methods: We reviewed 24 GCT of the distal radius in 23 patients (12 males: 11 females) with a mean age of 42 years at the time of surgery. Functional outcomes were collected including the Musculoskeletal Tumor Society Score (MSTS), QuickDash, the Visual Analog Scale (VAS), and the Patient Rated Wrist Evaluation (PRWE). The mean follow-up was 13 years. Results: Tumor grade included Campanacci Grade II (n = 14) and Grade III (n = 10). Treatment included extended intralesional curettage (n = 16) and wide excision (n = 8). Reconstruction mainly included bone grafting/cement (n = 16) or free vascularized fibula radiocarpal arthrodesis (n = 5). At most recent follow-up, there was no difference in MSTS, VAS, and PRWE (p > 0.05) between patients undergoing a joint sparing or arthrodesis. Patients undergoing arthrodesis had a lower QuickDASH score (13.7 vs. 20.8, p = 0.04). Conclusions: Treatment for GCT of the distal radius is individualized however in the setting of articular surface involvement, arthrodesis can lead to superior functional results at long-term follow-up.

Original languageEnglish (US)
Pages (from-to)798-803
Number of pages6
JournalJournal of Surgical Oncology
Issue number4
StatePublished - Sep 15 2022


  • bone tumor
  • giant cell tumor of bone
  • patient-reported outcomes
  • surgical treatment

ASJC Scopus subject areas

  • Surgery
  • Oncology


Dive into the research topics of 'Treatment of giant cell tumors of the distal radius: A long-term patient-reported outcomes study'. Together they form a unique fingerprint.

Cite this