Treatment of Acute Myocardial Infarction

Charles Beauchamp, Eric C. Westman, Joseph A. Govert, Howard S. Friedman, T. H. Hughes-Davies, William W. Rowe, Cindy L. Grines, William W. O'neill, Felix Zijlstra, Menko Jan de Boer, Harry Suryapranata, R. J. Gibbons, D. R. Holmes, G. S. Reeder

Research output: Contribution to journalLetterpeer-review

1 Scopus citations


To the Editor: “Referral filter” bias can affect the generalizability of the results of any clinical trial1. The three clinical trials comparing angioplasty with thrombolytic therapy in the March 11 issue of the Journal did not mention the referral filter that led to the enrolled samples24. Physicians have no way of knowing whether the study populations are similar to their own patients without a clinical description of the patients who were excluded. Could the authors comment on the number of patients excluded and the reasons for exclusion? To the Editor: It is difficult to draw any firm…

Original languageEnglish (US)
Pages (from-to)430-433
Number of pages4
JournalNew England Journal of Medicine
Issue number6
StatePublished - Aug 5 1993

ASJC Scopus subject areas

  • General Medicine


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