Transcutaneous partial pressure of oxygen after surgical wounds

Ian R. McPhail, Leslie T. Cooper, David O. Hodge, Miguel E. Cabanela, Thom W. Rooke

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Transcutaneous partial pressure of oxygen (TcPO2) predicts wound healing in critical ischemia. However, no studies have controlled for the effect of wounds on TcPO2. In this study, in 24 hip or knee arthroplasty cases without vascular disease, TcPO2 was measured preoperatively at the incision site, contralaterally, and at a reference site on the chest wall. The measurements were repeated at 2 days and 2 months postoperatively and compared. TcPO2, normal preoperatively, decreased at all sites on the second postoperative day (p < 0.001), with a trend toward a greater decrease at the wound (p = 0.09). All wounds healed, and TcPO2 returned to baseline at all sites 2 months postoperatively. In conclusion, acute surgical wounds are associated with a significant and widespread decrease in cutaneous TcPO2 in the setting of normal arterial perfusion. This decrease is likely multifactorial and deserves further investigation.

Original languageEnglish (US)
Pages (from-to)125-127
Number of pages3
JournalVascular Medicine
Issue number2
StatePublished - 2004


  • Microcirculation
  • Oximetry
  • Wound healing
  • Wounds

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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