TY - JOUR
T1 - Toward harmonization of strategies for investigating lucidity in AD/ADRD
T2 - A preliminary research framework
AU - Gilmore-Bykovskyi, Andrea
AU - Griffin, Joan M.
AU - Mueller, Kimberly D.
AU - Parnia, Sam
AU - Kolanowski, Ann
N1 - Publisher Copyright:
© 2022 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.
PY - 2023/1
Y1 - 2023/1
N2 - Episodes of lucidity (ELs) in Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD), have garnered increasing attention as an important area of research. Efforts to study lucidity suffer from a lack of clear definitional criteria, inconsistent conceptualization, and diverse approaches to operationalizing features of these events. To advance systematic investigation of ELs in AD/ADRD, there is a need for clarity and precision in labeling event attributes, markers, and specific measurement strategies that enable operational harmonization across distinct approaches to investigating the relatively broad and nascent phenomenon. To that end, we propose a preliminary research framework to guide harmonization of approaches to investigating ELs in AD/ADRD. Our goal is to provide an initial schematic that encourages uniform labeling of operational decisions about ELs.
AB - Episodes of lucidity (ELs) in Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD), have garnered increasing attention as an important area of research. Efforts to study lucidity suffer from a lack of clear definitional criteria, inconsistent conceptualization, and diverse approaches to operationalizing features of these events. To advance systematic investigation of ELs in AD/ADRD, there is a need for clarity and precision in labeling event attributes, markers, and specific measurement strategies that enable operational harmonization across distinct approaches to investigating the relatively broad and nascent phenomenon. To that end, we propose a preliminary research framework to guide harmonization of approaches to investigating ELs in AD/ADRD. Our goal is to provide an initial schematic that encourages uniform labeling of operational decisions about ELs.
UR - http://www.scopus.com/inward/record.url?scp=85132737819&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85132737819&partnerID=8YFLogxK
U2 - 10.1002/alz.12709
DO - 10.1002/alz.12709
M3 - Article
C2 - 35757902
AN - SCOPUS:85132737819
SN - 1552-5260
VL - 19
SP - 343
EP - 352
JO - Alzheimer's and Dementia
JF - Alzheimer's and Dementia
IS - 1
ER -