Tissue biopsy for the diagnosis of amyloidosis: experience from some centres

Merrill D. Benson, John L. Berk, Angela Dispenzieri, Thibaud Damy, Julian D. Gillmore, Bouke P. Hazenberg, Francesca Lavatelli, Maria M. Picken, Christoph Röcken, Stefan Schönland, Mitsuharu Ueda, Per Westermark

Research output: Contribution to journalArticlepeer-review


A reliable diagnosis of amyloidosis is usually based on a tissue biopsy. With increasing options for specific treatments of the different amyloid diseases, an exact and valid diagnosis including determination of the biochemical fibril nature is imperative. Biopsy sites as well as amyloid typing principles vary and this paper describes methods employed at some laboratories specialised in amyloidosis in Europe, Japan and USA.

Original languageEnglish (US)
Pages (from-to)8-13
Number of pages6
Issue number1
StatePublished - 2022


  • Amyloid
  • immunohistochemistry
  • mass spectrometry
  • method

ASJC Scopus subject areas

  • Internal Medicine


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