Time-of-arrival mapping at three-dimensional timeresolved contrast-enhanced MR angiography

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


This study was HIPAA compliant and institutional review board approved, and informed consent was obtained from all volunteers. The authors describe a method for generating a time-of-arrival (TOA) map of intravenously administered contrast material, as observed in a time series of three-dimensional (3D) contrast material-enhanced magnetic resonance (MR) angiograms. The method may enable visualization and interpretation, on one 3D image, of the temporal enhancement patterns that occur in the vasculature. Colorization of TOA values may further aid interpretation. The quality of the results depends not only on the adequacy of the frame rate, spatial resolution, and signal-to-noise ratio of the MR image acquisition method but also on the accuracy and clarity with which the leading edge of the contrast material bolus is depicted. The criteria for optimizing these parameters are described. The TOA mapping technique is demonstrated by using vascular studies of the hands, brain, and lower leg regions.

Original languageEnglish (US)
Pages (from-to)532-542
Number of pages11
Issue number2
StatePublished - Nov 2009

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Time-of-arrival mapping at three-dimensional timeresolved contrast-enhanced MR angiography'. Together they form a unique fingerprint.

Cite this