TY - JOUR
T1 - Thoracoamniotic shunting for fetal pleural effusions with hydrops
AU - Picone, Olivier
AU - Benachi, Alexandra
AU - Mandelbrot, Laurent
AU - Ruano, Rodrigo
AU - Dumez, Yves
AU - Dommergues, Marc
PY - 2004/12
Y1 - 2004/12
N2 - The purpose of this study was to evaluate perinatal outcome after thoracoamniotic shunting for fetal pleural effusions with hydrops. This was a retrospective study. Shunting was performed immediately after diagnosis and was successful in all 54 of the cases that were attempted. There were 7 pregnancy terminations, 9 in utero deaths, and 38 live births, of which 7 children died in the neonatal period and 31 children survived. Among the liveborn infants, 27 infants were delivered preterm (71%), of whom 7 infants (15%) had preterm premature rupture of membranes and 4 infants (8.5%) had chorioamnionitis. Perinatal death (23/54 infants; 43%) was related to underlying anomalies (7 cases), pulmonary hypoplasia (5 cases), chorioamnionitis (2 cases), or treatment failure for unknown reasons (9 cases). All 31 survivors had chylothorax; for 28 of the survivors, the chylothorax was primary, and for 3 survivors, the chylothorax was the result of right congenital diaphragmatic hernia, pulmonary sequestration, or Noonan syndrome. After the shunting, pleural effusion with hydrops has a 57% survival rate; premature delivery is the leading source of morbidity.
AB - The purpose of this study was to evaluate perinatal outcome after thoracoamniotic shunting for fetal pleural effusions with hydrops. This was a retrospective study. Shunting was performed immediately after diagnosis and was successful in all 54 of the cases that were attempted. There were 7 pregnancy terminations, 9 in utero deaths, and 38 live births, of which 7 children died in the neonatal period and 31 children survived. Among the liveborn infants, 27 infants were delivered preterm (71%), of whom 7 infants (15%) had preterm premature rupture of membranes and 4 infants (8.5%) had chorioamnionitis. Perinatal death (23/54 infants; 43%) was related to underlying anomalies (7 cases), pulmonary hypoplasia (5 cases), chorioamnionitis (2 cases), or treatment failure for unknown reasons (9 cases). All 31 survivors had chylothorax; for 28 of the survivors, the chylothorax was primary, and for 3 survivors, the chylothorax was the result of right congenital diaphragmatic hernia, pulmonary sequestration, or Noonan syndrome. After the shunting, pleural effusion with hydrops has a 57% survival rate; premature delivery is the leading source of morbidity.
KW - Chylothorax
KW - Fetal therapy
KW - Hydrops
KW - Pleural effusion
KW - Thoracoamniotic shunt
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UR - http://www.scopus.com/inward/citedby.url?scp=10044263012&partnerID=8YFLogxK
U2 - 10.1016/j.ajog.2004.05.016
DO - 10.1016/j.ajog.2004.05.016
M3 - Article
C2 - 15592290
AN - SCOPUS:10044263012
SN - 0002-9378
VL - 191
SP - 2047
EP - 2050
JO - American journal of obstetrics and gynecology
JF - American journal of obstetrics and gynecology
IS - 6
ER -