Thiopurine S-methyltransferase pharmacogenetics: Functional characterization of a novel rapidly degraded variant allozyme

Medicine & Life Sciences

• thiopurine methyltransferase 93%
• Pharmacogenetics 68%
• Isoenzymes 60%
• Proteasome Endopeptidase Complex 18%
• human TPMT protein 12%
• Autophagy 11%
• Viperidae 8%
• Reticulocytes 7%
• Molecular Dynamics Simulation 6%
• Proteins 6%
• Enzymes 6%
• Kidney Transplantation 5%
• Proteolysis 5%
• Single Nucleotide Polymorphism 5%
• Erythrocytes 4%
• Alleles 4%
• Rabbits 4%
• Cell Line 3%
• Pharmaceutical Preparations 2%

Chemical Compounds

• Thiopurine 100%
• Protein 6%
• Mammalian Cell 5%
• Enzyme Activity 4%
• Molecular Dynamics 4%
• Simulation 3%