The Use of Intravenous Nitroglycerin in Cardiovascular Disease

Allan S. Jaffe, Robert Roberts

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


The development of an intravenous form of nitroglycerin has further enhanced the role of nitrates in the therapy of cardiovascular disorders. This new preparation permits prompt initiation of therapy and rapid attainment of high systemic levels; because of its short half‐life, rapid dose titration is both feasible and safe. The antianginal effects of intravenous nitroglycerin are useful in the treatment of coronary vasospasm and unstable angina pectoris. Its hemodynamic effects are of benefit in the therapy of congestive heart failure and in the control of peri‐operative hypertension. Recent data suggest that, with appropriate monitoring, intravenous nitroglycerin can be safely administered to patients with evolving myocardial infarction to reduce the extent of myocardial damage. 1982 Pharmacotherapy Publications Inc.

Original languageEnglish (US)
Pages (from-to)273-278
Number of pages6
JournalPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
Issue number5
StatePublished - 1982

ASJC Scopus subject areas

  • Pharmacology (medical)


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