The treatment of ictal asystole with cardiac pacing

Brian D. Moseley, Gena R. Ghearing, Thomas M. Munger, Jeffrey W. Britton

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


Ictal asystole may contribute to seizure-related injury and mortality. The purpose of this study was to evaluate the effect of cardiac pacing on seizure-related injury rates in ictal asystole patients. A survey was conducted to determine seizure-related fall rate and other morbidity in all seven patients with ictal asystole who underwent cardiac pacing at our institution between 1990 and 2004. The rate of seizure-related falls and other morbidities before and after pacing were compared using the Wilcoxon rank-sum test. The mean fall rate was 3.28 falls/month pre-pacemaker implantation. Following pacemaker implantation, this was reduced to 0.005 falls/month (p = 0.001). Seizure-related fractures and motor vehicle accidents were also reduced following cardiac pacing. These findings may have implications in mitigating the potential morbidity associated with ictal asystole.

Original languageEnglish (US)
Pages (from-to)e16-e19
Issue number4
StatePublished - Apr 2011


  • Asystole
  • Epilepsy
  • Pacing

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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