The treatable dementia of sjögren's syndrome

Richard J. Caselli, Bernd W. Scheithauer, Carolyn A. Bowles, Max R. Trenerry, Fredric B. Meyer, Jeffrey S. Smigielski, Moses Rodriguez

Research output: Contribution to journalArticlepeer-review

74 Scopus citations


Progressive dementia developed during a 15‐month period in a 56‐year‐old woman with serologically and clinically documented primary Sjögren's syndrome. Findings from magnetic resonance imaging and angiography were normal, but a brain biopsy disclosed perivascular lymphocytic inflammation in leptomeningeal and parenchymal vessels. Treatment with high‐dose corticosteroids produced rapid and nearly complete resolution of the dementia.

Original languageEnglish (US)
Pages (from-to)98-101
Number of pages4
JournalAnnals of neurology
Issue number1
StatePublished - Jul 1991

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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