The Role of Magnetic Resonance Elastography in the Diagnosis of Noncirrhotic Portal Hypertension

Patrick J. Navin; Tolga Gidener; Alina M. Allen; Meng Yin; Naoki Takahashi; Michael S. Torbenson; Patrick S. Kamath; Richard L. Ehman; Sudhakar K. Venkatesh

doi:10.1016/j.cgh.2019.10.018

The Role of Magnetic Resonance Elastography in the Diagnosis of Noncirrhotic Portal Hypertension

Patrick J. Navin, Tolga Gidener, Alina M. Allen, Meng Yin, Naoki Takahashi, Michael S. Torbenson, Patrick S. Kamath, Richard L. Ehman, Sudhakar K. Venkatesh

Research output: Contribution to journal › Short survey › peer-review

2 Scopus citations

Abstract

Portal hypertension (PH) is defined as abnormal elevation of portal venous pressure with cirrhosis accounting for 90% of cases and 10% of cases classified as noncirrhotic PH (NCPH).¹^,² The differentiation of cirrhotic PH (CPH) from NCPH is difficult (Supplementary Figure 1), with recent research efforts focusing on noninvasive evidence of increased hepatic stiffness.^3,4 Magnetic resonance elastography (MRE) is an established imaging technique in the assessment of hepatic stiffness, and is now the most efficacious, noninvasive method to assess for hepatic fibrosis.^5–8 The aim of this study was to assess the ability of magnetic resonance imaging (MRI) and MRE to differentiate between CPH and NCPH.

Original language	English (US)
Pages (from-to)	3051-3053.e2
Journal	Clinical Gastroenterology and Hepatology
Volume	18
Issue number	13
DOIs	https://doi.org/10.1016/j.cgh.2019.10.018
State	Published - Dec 2020

ASJC Scopus subject areas

Hepatology
Gastroenterology

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@article{11b92156051241b5b1925aaca05dcc80,

title = "The Role of Magnetic Resonance Elastography in the Diagnosis of Noncirrhotic Portal Hypertension",

abstract = "Portal hypertension (PH) is defined as abnormal elevation of portal venous pressure with cirrhosis accounting for 90% of cases and 10% of cases classified as noncirrhotic PH (NCPH).1,2 The differentiation of cirrhotic PH (CPH) from NCPH is difficult (Supplementary Figure 1), with recent research efforts focusing on noninvasive evidence of increased hepatic stiffness.3,4 Magnetic resonance elastography (MRE) is an established imaging technique in the assessment of hepatic stiffness, and is now the most efficacious, noninvasive method to assess for hepatic fibrosis.5–8 The aim of this study was to assess the ability of magnetic resonance imaging (MRI) and MRE to differentiate between CPH and NCPH.",

author = "Navin, {Patrick J.} and Tolga Gidener and Allen, {Alina M.} and Meng Yin and Naoki Takahashi and Torbenson, {Michael S.} and Kamath, {Patrick S.} and Ehman, {Richard L.} and Venkatesh, {Sudhakar K.}",

note = "Publisher Copyright: {\textcopyright} 2020 AGA Institute",

year = "2020",

month = dec,

doi = "10.1016/j.cgh.2019.10.018",

language = "English (US)",

volume = "18",

pages = "3051--3053.e2",

journal = "Clinical Gastroenterology and Hepatology",

issn = "1542-3565",

publisher = "W.B. Saunders Ltd",

number = "13",

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TY - JOUR

T1 - The Role of Magnetic Resonance Elastography in the Diagnosis of Noncirrhotic Portal Hypertension

AU - Navin, Patrick J.

AU - Gidener, Tolga

AU - Allen, Alina M.

AU - Yin, Meng

AU - Takahashi, Naoki

AU - Torbenson, Michael S.

AU - Kamath, Patrick S.

AU - Ehman, Richard L.

AU - Venkatesh, Sudhakar K.

PY - 2020/12

Y1 - 2020/12

N2 - Portal hypertension (PH) is defined as abnormal elevation of portal venous pressure with cirrhosis accounting for 90% of cases and 10% of cases classified as noncirrhotic PH (NCPH).1,2 The differentiation of cirrhotic PH (CPH) from NCPH is difficult (Supplementary Figure 1), with recent research efforts focusing on noninvasive evidence of increased hepatic stiffness.3,4 Magnetic resonance elastography (MRE) is an established imaging technique in the assessment of hepatic stiffness, and is now the most efficacious, noninvasive method to assess for hepatic fibrosis.5–8 The aim of this study was to assess the ability of magnetic resonance imaging (MRI) and MRE to differentiate between CPH and NCPH.

AB - Portal hypertension (PH) is defined as abnormal elevation of portal venous pressure with cirrhosis accounting for 90% of cases and 10% of cases classified as noncirrhotic PH (NCPH).1,2 The differentiation of cirrhotic PH (CPH) from NCPH is difficult (Supplementary Figure 1), with recent research efforts focusing on noninvasive evidence of increased hepatic stiffness.3,4 Magnetic resonance elastography (MRE) is an established imaging technique in the assessment of hepatic stiffness, and is now the most efficacious, noninvasive method to assess for hepatic fibrosis.5–8 The aim of this study was to assess the ability of magnetic resonance imaging (MRI) and MRE to differentiate between CPH and NCPH.

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U2 - 10.1016/j.cgh.2019.10.018

DO - 10.1016/j.cgh.2019.10.018

M3 - Short survey

C2 - 31629882

AN - SCOPUS:85096202786

SN - 1542-3565

VL - 18

SP - 3051-3053.e2

JO - Clinical Gastroenterology and Hepatology

JF - Clinical Gastroenterology and Hepatology

IS - 13

ER -

The Role of Magnetic Resonance Elastography in the Diagnosis of Noncirrhotic Portal Hypertension

Abstract

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