The Role of Circulating Tumor DNA in Evaluating Minimal Residual Disease in Luminal Gastrointestinal Malignancies

Benjamin E. Ueberroth; Jeremy C. Jones; Tanios Bekaii-Saab

The Role of Circulating Tumor DNA in Evaluating Minimal Residual Disease in Luminal Gastrointestinal Malignancies

Benjamin E. Ueberroth, Jeremy C. Jones, Tanios Bekaii-Saab

Hematology/Oncology

Research output: Contribution to journal › Article › peer-review

Abstract

The analysis of circulating tumor DNA (ctDNA) has multiple uses in oncology. In the past few years, studies with vary-ing designs, methods, and quality have emerged that show promise for the use of ctDNA as a tool to detect minimal residual disease (MRD) across luminal gastrointestinal malignancies. This review of the current literature looks at ctDNA in relation to detecting MRD, predicting patient prognosis, and assessing risk for recurrence.

Original language	English (US)
Pages (from-to)	444-455
Number of pages	12
Journal	Clinical Advances in Hematology and Oncology
Volume	20
Issue number	7
State	Published - Jul 2022

Keywords

Circulating tumor DNA
MRD
gastrointestinal cancer
prognosis
residual disease

ASJC Scopus subject areas

Hematology
Oncology

Cite this

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abstract = "The analysis of circulating tumor DNA (ctDNA) has multiple uses in oncology. In the past few years, studies with vary-ing designs, methods, and quality have emerged that show promise for the use of ctDNA as a tool to detect minimal residual disease (MRD) across luminal gastrointestinal malignancies. This review of the current literature looks at ctDNA in relation to detecting MRD, predicting patient prognosis, and assessing risk for recurrence.",

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The Role of Circulating Tumor DNA in Evaluating Minimal Residual Disease in Luminal Gastrointestinal Malignancies

Abstract

Keywords

ASJC Scopus subject areas

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