The prevention of pneumococcal disease by vaccines: Promises and challenges

G. A. Poland

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


This article reviews the epidemiology of pneumococcal disease and the current data on pneumococcal vaccine efficacy, discusses promising new data regarding development of new protein-conjugate pneumococcal vaccines, and addresses controversies surrounding the widespread population use of these vaccines. Armed with these data, physicians, nurses, third party payers, and health care systems should develop systems and eliminate unintentional barriers so as to achieve widespread use of these life-saving vaccines. As history has demonstrated to us, control of pneumococcal disease is highly unlikely to occur from heavy investments in newer and ever more expensive antibiotics, as opposed to better methods of preventing disease through the rational and widespread population use of vaccines.

Original languageEnglish (US)
Pages (from-to)97-122
Number of pages26
JournalInfectious Disease Clinics of North America
Issue number1
StatePublished - 2001

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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