The impact of surgical resection on headache disability and quality of life in patients with colloid cyst

Lyonell Kone, Kaisorn L. Chaichana, Jordina Rincon-Torroella, Claire Snyman, Abhay Moghekar, Alfredo Quinones-Hinojosa

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Introduction Colloid cysts are histologically benign but can present with a broad spectrum of symptoms. A systematic review of the literature did not reveal any patient-centered data on the headache disability and quality of life (QoL) of these patients. Methods This is a retrospective cohort study of 187 colloid cyst patients from the Colloid Cyst Survival Group who completed a survey that included demographic data, clinical data, a modified QoL survey (SF36v2), and a headache disability inventory or index (HDI). Results Using multivariable linear regressions, we confirmed that the physical (PCS) and mental (MCS) components of SF-36 were significantly increased in the surgery group after adjustment for various baseline characteristics (p = 0.025; p = 0.006). Self-reported headache disability was significantly decreased with surgery when adjusted for the same baseline characteristics (p = 0.02). Finally, patients with an incidental diagnosis of colloid cyst reported similar benefits from surgery in PCS, MCS and HDI. Conclusion Our results suggest that colloid cyst patients who underwent a surgical resection self-report a better QoL and less headache disability compared with patients who did not undergo surgery. Future prospective studies with baseline measures of QoL are indicated to confirm our findings.

Original languageEnglish (US)
Pages (from-to)442-451
Number of pages10
Issue number5
StatePublished - Apr 1 2017
Externally publishedYes


  • Colloid cyst
  • HDI
  • headaches
  • quality of life
  • SF-36
  • surgery

ASJC Scopus subject areas

  • Clinical Neurology


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