The establishment of public health policies and the burden of non-alcoholic fatty liver disease in the Americas

Luis Antonio Díaz; Eduardo Fuentes-López; Gustavo Ayares; Francisco Idalsoaga; Jorge Arnold; Andrea Márquez-Lomas; Carolina A. Ramírez; María Paz Medel; Francisca Viñuela; Lucas Lacalle; Juan Pablo Roblero; Catterina Ferreccio; Mariana Lazo; Mayur Brahmania; Ashwani K. Singal; Melisa Dirchwolf; Nahum Méndez-Sánchez; Norberto Chavez-Tapia; Patricia Guerra; Juan Carlos Restrepo; Claudia P. Oliveira; Julissa Lombardo; Abel Sánchez; Martín Elizondo; Martín Tagle; Martín Padilla; Marco Sánchez; Enrique Carrera; Marcos Girala; Omega Chery; Marlen Castellanos-Fernández; Francisco Barrera; Jeffrey V. Lazarus; Patrick S. Kamath; Ramon Bataller; Marco Arrese; Juan Pablo Arab

doi:10.1016/S2468-1253(22)00008-5

The establishment of public health policies and the burden of non-alcoholic fatty liver disease in the Americas

Luis Antonio Díaz, Eduardo Fuentes-López, Gustavo Ayares, Francisco Idalsoaga, Jorge Arnold, Andrea Márquez-Lomas, Carolina A. Ramírez, María Paz Medel, Francisca Viñuela, Lucas Lacalle, Juan Pablo Roblero, Catterina Ferreccio, Mariana Lazo, Mayur Brahmania, Ashwani K. Singal, Melisa Dirchwolf, Nahum Méndez-Sánchez, Norberto Chavez-Tapia, Patricia Guerra, Juan Carlos RestrepoClaudia P. Oliveira, Julissa Lombardo, Abel Sánchez, Martín Elizondo, Martín Tagle, Martín Padilla, Marco Sánchez, Enrique Carrera, Marcos Girala, Omega Chery, Marlen Castellanos-Fernández, Francisco Barrera, Jeffrey V. Lazarus, Patrick S. Kamath, Ramon Bataller, Marco Arrese, Juan Pablo Arab

Gastroenterology and Hepatology

Research output: Contribution to journal › Review article › peer-review

Abstract

Non-alcoholic fatty liver disease (NAFLD) affects 20–25% of the general population and is associated with morbidity, increased mortality, and elevated health-care costs. Most NAFLD risk factors are modifiable and, therefore, potentially amenable to being reduced by public health policies. To date, there is no information about NAFLD-related public health policies in the Americas. In this study, we analysed data from 17 American countries and found that none have established national public health policies to decrease NAFLD-related burden. There is notable heterogeneity in the existence of public health policies to prevent NAFLD-related conditions. The most common public health policies were related to diabetes (15 [88%] countries), hypertension (14 [82%] countries), cardiovascular diseases (14 [82%] countries), obesity (nine [53%] countries), and dyslipidaemia (six [35%] of countries). Only seven (41%) countries had a registry of the burden of NAFLD, and efforts to raise awareness in the Americas were scarce. The implementation of public health policies are urgently needed in the Americas to decrease the burden of NAFLD.

Original language	English (US)
Pages (from-to)	552-559
Number of pages	8
Journal	The Lancet Gastroenterology and Hepatology
Volume	7
Issue number	6
DOIs	https://doi.org/10.1016/S2468-1253(22)00008-5
State	Published - Jun 2022

ASJC Scopus subject areas

Hepatology
Gastroenterology

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10.1016/S2468-1253(22)00008-5

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Díaz, L. A., Fuentes-López, E., Ayares, G., Idalsoaga, F., Arnold, J., Márquez-Lomas, A., Ramírez, C. A., Medel, M. P., Viñuela, F., Lacalle, L., Roblero, J. P., Ferreccio, C., Lazo, M., Brahmania, M., Singal, A. K., Dirchwolf, M., Méndez-Sánchez, N., Chavez-Tapia, N., Guerra, P., ... Arab, J. P. (2022). The establishment of public health policies and the burden of non-alcoholic fatty liver disease in the Americas. The Lancet Gastroenterology and Hepatology, 7(6), 552-559. https://doi.org/10.1016/S2468-1253(22)00008-5

Díaz, LA, Fuentes-López, E, Ayares, G, Idalsoaga, F, Arnold, J, Márquez-Lomas, A, Ramírez, CA, Medel, MP, Viñuela, F, Lacalle, L, Roblero, JP, Ferreccio, C, Lazo, M, Brahmania, M, Singal, AK, Dirchwolf, M, Méndez-Sánchez, N, Chavez-Tapia, N, Guerra, P, Restrepo, JC, Oliveira, CP, Lombardo, J, Sánchez, A, Elizondo, M, Tagle, M, Padilla, M, Sánchez, M, Carrera, E, Girala, M, Chery, O, Castellanos-Fernández, M, Barrera, F, Lazarus, JV, Kamath, PS, Bataller, R, Arrese, M & Arab, JP 2022, 'The establishment of public health policies and the burden of non-alcoholic fatty liver disease in the Americas', The Lancet Gastroenterology and Hepatology, vol. 7, no. 6, pp. 552-559. https://doi.org/10.1016/S2468-1253(22)00008-5

@article{56781d22eeeb4f2481aecd23428af92d,

title = "The establishment of public health policies and the burden of non-alcoholic fatty liver disease in the Americas",

abstract = "Non-alcoholic fatty liver disease (NAFLD) affects 20–25% of the general population and is associated with morbidity, increased mortality, and elevated health-care costs. Most NAFLD risk factors are modifiable and, therefore, potentially amenable to being reduced by public health policies. To date, there is no information about NAFLD-related public health policies in the Americas. In this study, we analysed data from 17 American countries and found that none have established national public health policies to decrease NAFLD-related burden. There is notable heterogeneity in the existence of public health policies to prevent NAFLD-related conditions. The most common public health policies were related to diabetes (15 [88%] countries), hypertension (14 [82%] countries), cardiovascular diseases (14 [82%] countries), obesity (nine [53%] countries), and dyslipidaemia (six [35%] of countries). Only seven (41%) countries had a registry of the burden of NAFLD, and efforts to raise awareness in the Americas were scarce. The implementation of public health policies are urgently needed in the Americas to decrease the burden of NAFLD.",

author = "D{\'i}az, {Luis Antonio} and Eduardo Fuentes-L{\'o}pez and Gustavo Ayares and Francisco Idalsoaga and Jorge Arnold and Andrea M{\'a}rquez-Lomas and Ram{\'i}rez, {Carolina A.} and Medel, {Mar{\'i}a Paz} and Francisca Vi{\~n}uela and Lucas Lacalle and Roblero, {Juan Pablo} and Catterina Ferreccio and Mariana Lazo and Mayur Brahmania and Singal, {Ashwani K.} and Melisa Dirchwolf and Nahum M{\'e}ndez-S{\'a}nchez and Norberto Chavez-Tapia and Patricia Guerra and Restrepo, {Juan Carlos} and Oliveira, {Claudia P.} and Julissa Lombardo and Abel S{\'a}nchez and Mart{\'i}n Elizondo and Mart{\'i}n Tagle and Mart{\'i}n Padilla and Marco S{\'a}nchez and Enrique Carrera and Marcos Girala and Omega Chery and Marlen Castellanos-Fern{\'a}ndez and Francisco Barrera and Lazarus, {Jeffrey V.} and Kamath, {Patrick S.} and Ramon Bataller and Marco Arrese and Arab, {Juan Pablo}",

note = "Funding Information: JPA, FB, MA, and CF receive support from the Chilean Government through the Fondo Nacional de Desarrollo Cient{\'i}fico y Tecnol{\'o}gico (FONDECYT 1200227 to JPA, 1191183 to FB, 1191145 to MA, and 1212066 to CF), and the Agencia Nacional de Investigaci{\'o}n y Desarrollo, through the ANID ACE 210009 grant. RB is recipient of National Institute on Alcohol Abuse and Alcoholism U01AA021908 and U01AA020821. JVL acknowledges support to ISGlobal from the Spanish Ministry of Science, Innovation and Universities through the “Centro de Excelencia Severo Ochoa 2019-2023” Programme (CEX2018-000806-S), and from the Government of Catalonia, Spain, through the CERCA Programme. Funding Information: JPA, FB, MA, and CF receive support from the Chilean Government through the Fondo Nacional de Desarrollo Cient{\'i}fico y Tecnol{\'o}gico (FONDECYT 1200227 to JPA, 1191183 to FB, 1191145 to MA, and 1212066 to CF), and the Agencia Nacional de Investigaci{\'o}n y Desarrollo, through the ANID ACE 210009 grant. RB is recipient of National Institute on Alcohol Abuse and Alcoholism U01AA021908 and U01AA020821. JVL acknowledges support to ISGlobal from the Spanish Ministry of Science, Innovation and Universities through the “Centro de Excelencia Severo Ochoa 2019-2023” Programme (CEX2018-000806-S), and from the Government of Catalonia, Spain, through the CERCA Programme. Publisher Copyright: {\textcopyright} 2022 Elsevier Ltd",

year = "2022",

month = jun,

doi = "10.1016/S2468-1253(22)00008-5",

language = "English (US)",

volume = "7",

pages = "552--559",

journal = "The Lancet Gastroenterology and Hepatology",

issn = "2468-1253",

publisher = "Elsevier Limited",

number = "6",

}

TY - JOUR

T1 - The establishment of public health policies and the burden of non-alcoholic fatty liver disease in the Americas

AU - Díaz, Luis Antonio

AU - Fuentes-López, Eduardo

AU - Ayares, Gustavo

AU - Idalsoaga, Francisco

AU - Arnold, Jorge

AU - Márquez-Lomas, Andrea

AU - Ramírez, Carolina A.

AU - Medel, María Paz

AU - Viñuela, Francisca

AU - Lacalle, Lucas

AU - Roblero, Juan Pablo

AU - Ferreccio, Catterina

AU - Lazo, Mariana

AU - Brahmania, Mayur

AU - Singal, Ashwani K.

AU - Dirchwolf, Melisa

AU - Méndez-Sánchez, Nahum

AU - Chavez-Tapia, Norberto

AU - Guerra, Patricia

AU - Restrepo, Juan Carlos

AU - Oliveira, Claudia P.

AU - Lombardo, Julissa

AU - Sánchez, Abel

AU - Elizondo, Martín

AU - Tagle, Martín

AU - Padilla, Martín

AU - Sánchez, Marco

AU - Carrera, Enrique

AU - Girala, Marcos

AU - Chery, Omega

AU - Castellanos-Fernández, Marlen

AU - Barrera, Francisco

AU - Lazarus, Jeffrey V.

AU - Kamath, Patrick S.

AU - Bataller, Ramon

AU - Arrese, Marco

AU - Arab, Juan Pablo

N1 - Funding Information: JPA, FB, MA, and CF receive support from the Chilean Government through the Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT 1200227 to JPA, 1191183 to FB, 1191145 to MA, and 1212066 to CF), and the Agencia Nacional de Investigación y Desarrollo, through the ANID ACE 210009 grant. RB is recipient of National Institute on Alcohol Abuse and Alcoholism U01AA021908 and U01AA020821. JVL acknowledges support to ISGlobal from the Spanish Ministry of Science, Innovation and Universities through the “Centro de Excelencia Severo Ochoa 2019-2023” Programme (CEX2018-000806-S), and from the Government of Catalonia, Spain, through the CERCA Programme. Funding Information: JPA, FB, MA, and CF receive support from the Chilean Government through the Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT 1200227 to JPA, 1191183 to FB, 1191145 to MA, and 1212066 to CF), and the Agencia Nacional de Investigación y Desarrollo, through the ANID ACE 210009 grant. RB is recipient of National Institute on Alcohol Abuse and Alcoholism U01AA021908 and U01AA020821. JVL acknowledges support to ISGlobal from the Spanish Ministry of Science, Innovation and Universities through the “Centro de Excelencia Severo Ochoa 2019-2023” Programme (CEX2018-000806-S), and from the Government of Catalonia, Spain, through the CERCA Programme. Publisher Copyright: © 2022 Elsevier Ltd

PY - 2022/6

Y1 - 2022/6

N2 - Non-alcoholic fatty liver disease (NAFLD) affects 20–25% of the general population and is associated with morbidity, increased mortality, and elevated health-care costs. Most NAFLD risk factors are modifiable and, therefore, potentially amenable to being reduced by public health policies. To date, there is no information about NAFLD-related public health policies in the Americas. In this study, we analysed data from 17 American countries and found that none have established national public health policies to decrease NAFLD-related burden. There is notable heterogeneity in the existence of public health policies to prevent NAFLD-related conditions. The most common public health policies were related to diabetes (15 [88%] countries), hypertension (14 [82%] countries), cardiovascular diseases (14 [82%] countries), obesity (nine [53%] countries), and dyslipidaemia (six [35%] of countries). Only seven (41%) countries had a registry of the burden of NAFLD, and efforts to raise awareness in the Americas were scarce. The implementation of public health policies are urgently needed in the Americas to decrease the burden of NAFLD.

AB - Non-alcoholic fatty liver disease (NAFLD) affects 20–25% of the general population and is associated with morbidity, increased mortality, and elevated health-care costs. Most NAFLD risk factors are modifiable and, therefore, potentially amenable to being reduced by public health policies. To date, there is no information about NAFLD-related public health policies in the Americas. In this study, we analysed data from 17 American countries and found that none have established national public health policies to decrease NAFLD-related burden. There is notable heterogeneity in the existence of public health policies to prevent NAFLD-related conditions. The most common public health policies were related to diabetes (15 [88%] countries), hypertension (14 [82%] countries), cardiovascular diseases (14 [82%] countries), obesity (nine [53%] countries), and dyslipidaemia (six [35%] of countries). Only seven (41%) countries had a registry of the burden of NAFLD, and efforts to raise awareness in the Americas were scarce. The implementation of public health policies are urgently needed in the Americas to decrease the burden of NAFLD.

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DO - 10.1016/S2468-1253(22)00008-5

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AN - SCOPUS:85129962396

SN - 2468-1253

VL - 7

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JO - The Lancet Gastroenterology and Hepatology

JF - The Lancet Gastroenterology and Hepatology

IS - 6

ER -

The establishment of public health policies and the burden of non-alcoholic fatty liver disease in the Americas

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