The effect of magnification on sonographically measured nerve cross-sectional area

Elena J. Jelsing, James C. Presley, Eugene Maida, Nicholas J. Hangiandreou, Jay Smith

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Introduction: The primary aim of this investigation was to determine whether use of write-zoom magnification affects sonographically determined cross-sectional area (CSA) of peripheral nerves. Methods: CSAs of the median (MN) and posterior interosseous (PIN) nerves were measured in 22 limbs from 11 asymptomatic volunteers using both standard imaging and write-zoom magnification. CSA measurements were repeated on the same images 1 week later. Results: The average CSA of write-zoomed images for the MN was significantly larger at both measurement sessions (week 1: 11.1 mm2 write-zoom vs. 10.0 mm2 standard, P=0.019; week 2: 11.8 mm2 vs. 10.4 mm2, P=0.023). Similar differences were noted for the PIN (week 1: 2.3 mm2 vs. 1.9 mm2, P=0.002; week 2: 2.5 mm2 vs. 1.9 mm2, P=0.001). Conclusions: Write-zoom magnification may significantly increase the measured CSA of peripheral nerves. These changes appear to be more substantial when smaller nerves are measured.

Original languageEnglish (US)
Pages (from-to)30-34
Number of pages5
JournalMuscle and Nerve
Issue number1
StatePublished - Jan 1 2015


  • Carpal tunnel syndrome
  • Cross-sectional area
  • Peripheral nerve
  • Posterior interosseous nerve ultrasound

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)


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