The effect of a silane coupling agent on the bond strength of bone cement and cobalt-chrome alloy

Scott A. Yerby, Adam F. Paal, Phillip M. Young, Gary S. Beaupré, Kevin L. Ohashi, Stuart B. Goodman

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Debonding of the cement-implant interface has been hypothesized to be the leading initial indicator of failed total hip prostheses. Many attempts have been made to increase the bond strength of this interface by precoating the implant, increasing the implant's surface roughness, and creating macro- grooves or channels on the implant. However, each of these approaches introduces new complications. This study introduces a unique silane coupling agent used to chemically bond the bone cement to the implant. Cylindrical cobalt-chrome samples were treated with the silane coupling agent, bonded to polymethylmethacrylate, and pushed out to failure. The mean shear strengths were compared to the failure strengths of untreated samples. Half of the specimens were tested immediately following cement curing, and the other half were tested after immersion in saline solution for 60 days. The mean shear strength of the silane-coated samples ranged from 18.2 to 24.1 MPa, and the mean shear strength of the uncoated samples ranged from 7.6 to 15.0 MPa. The increase in strength following silane coating noted in this study may increase the longevity of the implant by decreasing debonding at the interface and, therefore, subsequent failure due to loosening.

Original languageEnglish (US)
Pages (from-to)127-133
Number of pages7
JournalJournal of Biomedical Materials Research
Issue number1
StatePublished - Jan 2000


  • Cobalt-chrome
  • Interface
  • Polymethylmethacrylate
  • Shear strength
  • Silane

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering


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