TY - JOUR
T1 - The Current Approach to Diagnosis and Management of Left Ventricular Noncompaction Cardiomyopathy
T2 - Review of the Literature
AU - Bennett, Courtney E.
AU - Freudenberger, Ronald
N1 - Publisher Copyright:
© 2016 Courtney E. Bennett and Ronald Freudenberger.
PY - 2016
Y1 - 2016
N2 - Isolated left ventricular noncompaction (LVNC) is a genetic cardiomyopathy characterized by prominent ventricular trabeculations and deep intertrabecular recesses, or sinusoids, in communication with the left ventricular cavity. The low prevalence of patients with this cardiomyopathy presents a unique challenge for large, prospective trials to assess its pathogenesis, management, and outcomes. In this paper we review the embryology and genetics of LVNC, the diagnostic approach, and propose a management approach based on the current literature available.
AB - Isolated left ventricular noncompaction (LVNC) is a genetic cardiomyopathy characterized by prominent ventricular trabeculations and deep intertrabecular recesses, or sinusoids, in communication with the left ventricular cavity. The low prevalence of patients with this cardiomyopathy presents a unique challenge for large, prospective trials to assess its pathogenesis, management, and outcomes. In this paper we review the embryology and genetics of LVNC, the diagnostic approach, and propose a management approach based on the current literature available.
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U2 - 10.1155/2016/5172308
DO - 10.1155/2016/5172308
M3 - Review article
AN - SCOPUS:84962675806
SN - 2090-8016
VL - 2016
JO - Cardiology Research and Practice
JF - Cardiology Research and Practice
M1 - 5172308
ER -