The consequences of not following a cardiac diet: Fatal forty DDI: Clopidogrel, omeprazole, CYP2C19

Kristen B. McCullough; Wayne T. Nicholson

doi:10.1007/978-1-4614-7495-1_150

The consequences of not following a cardiac diet: Fatal forty DDI: Clopidogrel, omeprazole, CYP2C19

Kristen B. McCullough, Wayne T. Nicholson

Anesthesiology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This case discusses a pharmacokinetic interaction between clopidogrel and omeprazole, resulting in a decreased antiplatelet effect of clopidogrel. Clopidogrel is a cytochrome P450 2C19 substrate and omeprazole is a 2C19 inhibitor.

Original language	English (US)
Title of host publication	A Case Approach to Perioperative Drug-Drug Interactions
Publisher	Springer New York
Pages	675-679
Number of pages	5
ISBN (Electronic)	9781461474951
ISBN (Print)	9781461474944
DOIs	https://doi.org/10.1007/978-1-4614-7495-1_150
State	Published - Sep 15 2015

ASJC Scopus subject areas

General Medicine

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10.1007/978-1-4614-7495-1_150

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The consequences of not following a cardiac diet: Fatal forty DDI: Clopidogrel, omeprazole, CYP2C19

Abstract

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